Losartan potassium

Losartan Potassium (CAS 124750-99-8) is a pharmaceutical active ingredient and potassium salt compound known under trade names including Cozaar and Zaart, and by development codes MK-954 and DuP-753. It carries no assigned E-code and is classified under HS code 2933290000 within the broader category of pharmaceutical intermediates.

In pharmaceutical manufacturing, Losartan Potassium serves primarily as an active pharmaceutical ingredient in antihypertensive drug formulations, where it functions by selectively blocking angiotensin II receptors to reduce vascular resistance. Research applications also explore its antimicrobial properties, where it disrupts microbial membrane function, supporting its evaluation as a preservation-relevant compound in formulation development.

Losartan Potassium is supplied as a white to off-white crystalline powder meeting pharmaceutical-grade specifications aligned with Ph.Eur. and USP monograph standards. It is subject to REACH registration requirements for EU supply. Procurement quantities are available in sealed, moisture-controlled packaging appropriate for active pharmaceutical ingredient handling.