Mesalazine
CAS 89-57-6
EC 201-919-1
Formula C7H7NO3
MW 153.14 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & Cosmetics Preservation & BiocideUV Protection & Stabilization
Description
Mesalazine (CAS 89-57-6), also known as mesalamine and 5-aminosalicylic acid (5-ASA), is an aminosalicylate compound used as a pharmaceutical intermediate and functional ingredient in personal care formulations. It carries no assigned E-code and is identified under EC 201-919-1 with HS code 29225000.
In pharmaceutical manufacturing, mesalazine serves as the active substance in anti-inflammatory drug products targeting intestinal conditions, functioning by inhibiting prostaglandin synthesis locally in mucosal tissue. In cosmetic formulations, it acts as a UV absorber and skin conditioner, where its phenolic structure enables absorption of UV radiation and interaction with skin surface proteins.
Mesalazine is supplied as off-white crystals meeting Ph.Eur. monograph specifications, with REACH compliance documentation available for EU procurement. Standard packaging formats suit both laboratory-scale and bulk industrial quantities. Buyers should confirm grade suitability against their specific pharmaceutical or cosmetic application requirements prior to ordering.
In pharmaceutical manufacturing, mesalazine serves as the active substance in anti-inflammatory drug products targeting intestinal conditions, functioning by inhibiting prostaglandin synthesis locally in mucosal tissue. In cosmetic formulations, it acts as a UV absorber and skin conditioner, where its phenolic structure enables absorption of UV radiation and interaction with skin surface proteins.
Mesalazine is supplied as off-white crystals meeting Ph.Eur. monograph specifications, with REACH compliance documentation available for EU procurement. Standard packaging formats suit both laboratory-scale and bulk industrial quantities. Buyers should confirm grade suitability against their specific pharmaceutical or cosmetic application requirements prior to ordering.
Physical Properties
| Melting Point | 283 °C |
| Boiling Point | 276.03°C (rough estimate) |
| Density | 1.5 g/cm³ |
| Flash Point | 279-281°C |
| Appearance | Off-White Crystals |
| Color | off-white to gray |
| Form | tablets |
| Water Solubility | <0.1 g/100 mL at 21 ºC |
| Vapor Pressure | 0Pa at 25℃ |
| Refractive Index | 1.5500 (estimate) |
| pH | 4.0-4.1 (0.8g/l, H2O, 20℃) |
| Log P | 0.98 at 25℃ |
Safety & Handling (Learn More)
Warning GHS07
H
H315H317H319H335H412
P
P261P264P271P272P273P280P319P321P405P501P264+P265P302+P352P304+P340P332+P317P333+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29225000 |
| WGK (Germany) | 2 |
Other Names
5-Aminosalicylic Acid5-amino-2-hydroxybenzoic acidPentasa®5-ASAAsacolPentasaMesalamineIFLAB-BB F1918-0003
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Raw Materials
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