SoleChem

Mesalazine

CAS 89-57-6
EC 201-919-1
Formula C7H7NO3
MW 153.14 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & Cosmetics Preservation & BiocideUV Protection & Stabilization

Description

Mesalazine (CAS 89-57-6), also known as mesalamine and 5-aminosalicylic acid (5-ASA), is an aminosalicylate compound used as a pharmaceutical intermediate and functional ingredient in personal care formulations. It carries no assigned E-code and is identified under EC 201-919-1 with HS code 29225000.

In pharmaceutical manufacturing, mesalazine serves as the active substance in anti-inflammatory drug products targeting intestinal conditions, functioning by inhibiting prostaglandin synthesis locally in mucosal tissue. In cosmetic formulations, it acts as a UV absorber and skin conditioner, where its phenolic structure enables absorption of UV radiation and interaction with skin surface proteins.

Mesalazine is supplied as off-white crystals meeting Ph.Eur. monograph specifications, with REACH compliance documentation available for EU procurement. Standard packaging formats suit both laboratory-scale and bulk industrial quantities. Buyers should confirm grade suitability against their specific pharmaceutical or cosmetic application requirements prior to ordering.

Physical Properties

Melting Point 283 °C
Boiling Point 276.03°C (rough estimate)
Density 1.5 g/cm³
Flash Point 279-281°C
Appearance Off-White Crystals
Color off-white to gray
Form tablets
Water Solubility <0.1 g/100 mL at 21 ºC
Vapor Pressure 0Pa at 25℃
Refractive Index 1.5500 (estimate)
pH 4.0-4.1 (0.8g/l, H2O, 20℃)
Log P 0.98 at 25℃

Safety & Handling (Learn More)

Warning GHS07
H
H315H317H319H335H412
P
P261P264P271P272P273P280P319P321P405P501P264+P265P302+P352P304+P340P332+P317P333+P317P337+P317P362+P364P403+P233P305+P351+P338

Trade & Regulatory

HS Code 29225000
WGK (Germany) 2

Other Names

5-Aminosalicylic Acid5-amino-2-hydroxybenzoic acidPentasa®5-ASAAsacolPentasaMesalamineIFLAB-BB F1918-0003

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