Metformin hydrochloride

Metformin hydrochloride (CAS 1115-70-4) is a biguanide compound supplied as a pharmaceutical-grade active ingredient, commercially recognised under trade names including Glucophage, Diabex, Diabetosan, and Meguan. It carries no assigned E-code and is classified under HS code 29252900 within the pharmaceutical intermediates category.

In antidiabetic drug manufacturing, metformin hydrochloride serves as the active pharmaceutical ingredient in oral solid dose formulations, where it reduces hepatic glucose production and improves peripheral insulin sensitivity. It is also used as a reference standard and process intermediate in API synthesis workflows and analytical method development within pharmaceutical R&D environments.

This material is available in Ph.Eur.- and USP-compliant grades as a crystalline powder, supporting both finished dosage form production and intermediate synthesis. Supplied in accordance with REACH regulations, it is typically offered in sealed pharmaceutical-grade packaging with full batch documentation, CoA, and impurity profiling to meet GMP procurement requirements.