Methyl nicotinate
CAS 93-60-7
EC 202-261-8
Formula C7H7NO2
MW 137.14 g/mol
Pharmaceutical Intermediates Personal Care & CosmeticsPharmaceuticals & HealthcareFood & Nutrition Flavoring & AcidulantAntioxidant & StabilizerCatalysis
Description
Methyl nicotinate (CAS 93-60-7) is the methyl ester of nicotinic acid, also known as niacin methyl ester, FEMA 3709, and Methyl Nicotinate DAC. It carries no E-code designation and is classified under pharmaceutical intermediates with the molecular formula C7H7NO2.
In pharmaceutical and cosmetic formulations, methyl nicotinate acts as a vasodilator by triggering prostaglandin-mediated skin flushing, making it a functional active in topical circulation-enhancing products. In food applications, it contributes pyridine-type flavor notes at controlled concentrations, and it serves as a reaction intermediate in the synthesis of active pharmaceutical ingredients.
Methyl nicotinate is available in pharmaceutical-grade and food-grade forms, with compliance references including Ph.Eur. and FCC standards where applicable. The substance is registered under REACH (EC 202-261-8) and classified under HS code 29333999. Packaging formats typically range from kilogram quantities to bulk drums depending on grade and application requirements.
In pharmaceutical and cosmetic formulations, methyl nicotinate acts as a vasodilator by triggering prostaglandin-mediated skin flushing, making it a functional active in topical circulation-enhancing products. In food applications, it contributes pyridine-type flavor notes at controlled concentrations, and it serves as a reaction intermediate in the synthesis of active pharmaceutical ingredients.
Methyl nicotinate is available in pharmaceutical-grade and food-grade forms, with compliance references including Ph.Eur. and FCC standards where applicable. The substance is registered under REACH (EC 202-261-8) and classified under HS code 29333999. Packaging formats typically range from kilogram quantities to bulk drums depending on grade and application requirements.
Physical Properties
| Melting Point | 42.5 °C |
| Boiling Point | 102-104 °C @ Press: 15 Torr |
| Density | 1.2528 (rough estimate) |
| Flash Point | 204 °F |
| Appearance | white to brownish crystals or crystalline powder |
| Color | White to brownish |
| Odor | at 10.00 % in dipropylene glycol. warm herbal tobacco |
| Form | Crystals or Crystalline Powder |
| Water Solubility | NEGLIGIBLE |
| Vapor Pressure | 0.4 hPa (25 °C) |
| Refractive Index | 1.5323 (estimate) |
| Log P | 0.68 at 25℃ |
Safety & Handling (Learn More)
Warning GHS07
H
H315H319
P
P264P280P321P264+P265P302+P352P332+P317P337+P317P362+P364P305+P351+P338
Trade & Regulatory
| HS Code | 29333999 |
| WGK (Germany) | 3 |
Other Names
Methyl Pyridine-3-CarboxylateHeat sprayMethylnicotinateNicomethNIACIN METHYL ESTERMETHYL NICOTINATE DAC
Related Products
Derivatives
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