Monothioglycerol

Monothioglycerol (CAS 96-27-5), also known as thioglycerol or thioglycerin and sold under the trade name Thiovanol, is a sulfur-containing diol with no assigned E-code. It combines a thiol group with two hydroxyl groups in a single molecule, giving it both reducing and moisture-retaining properties.

In pharmaceutical formulations, monothioglycerol acts as an antioxidant reducing agent, protecting active ingredients from oxidative degradation by donating electrons to free radicals. In personal care, it functions as a humectant by binding water within the skin matrix. It also serves as a crosslinker in polymer chemistry, forming disulfide bridges that modify gel network structure.

Monothioglycerol is available in pharmaceutical grade (Ph.Eur. compliant) and food-grade (FCC compliant) specifications, supporting use across regulated industries. It falls under REACH registration requirements for EU supply. Standard packaging includes drums and intermediate bulk containers, with documentation available to meet pharmaceutical supplier qualification requirements.