N-Acetyl-L-glutamic acid

N-Acetyl-L-glutamic acid (CAS 1188-37-0) is a naturally occurring derivative of L-glutamic acid in which the amino group is acetylated. It is commercially referenced under the abbreviations AC-GLU-OH, N-AC-L-GLU, and N-Acetyl-L-Glu, and carries no assigned E-code. It is classified under HS code 29241900.

In personal care formulations, it functions as a humectant and skin conditioner by binding water within the stratum corneum, supporting moisture retention without occlusion. In pharmaceutical buffering systems, it stabilises pH in aqueous preparations through its carboxylic acid and acetamide groups, making it suitable for topical and injectable formulation development.

N-Acetyl-L-glutamic acid is supplied as a white crystalline powder in cosmetic and pharmaceutical grades, compliant with REACH regulations. Buyers should confirm alignment with Ph.Eur. or FCC monograph requirements depending on end-use. Standard packaging formats include 1 kg, 5 kg, and 25 kg quantities.