n-Boc-hydroxylamine

N-BOC-Hydroxylamine (CAS 36016-38-3) is a protected hydroxylamine reagent commonly abbreviated as Boc-NHOH or Boc-NH-OH, also referred to as t-butyl N-hydroxycarbamate. It carries no assigned E-code. The Boc protecting group shields the reactive nitrogen-oxygen functionality, enabling controlled chemistry in multi-step synthesis workflows.

In pharmaceutical intermediate synthesis, N-BOC-Hydroxylamine serves as a building block for hydroxamic acid derivatives, where the Boc group is selectively removed under mild acidic conditions to release free hydroxylamine for subsequent coupling. It also functions as a catalyst and antimicrobial agent in personal care formulations, where its hydroxylamine moiety interferes with microbial enzymatic activity.

This compound is supplied as a white to light pink crystalline powder meeting pharmaceutical-grade specifications and falls under REACH registration obligations within the EU. It is classified under HS code 29280090 for customs purposes. Standard packaging formats include laboratory-scale quantities through to bulk consignments for industrial procurement.