n-Methyl-2-pyrrolidinone
CAS 872-50-4
EC 212-828-1
Formula C5H9NO
MW 99.13 g/mol
Solvents Personal Care & CosmeticsElectronicsPharmaceuticals & HealthcarePlastics & Polymers Humectant & MoisturizingSolvent & CarrierPreservation & BiocideUV Protection & Stabilization
Description
N-Methyl-2-pyrrolidinone (NMP, CAS 872-50-4) is a water-miscible polar aprotic solvent also known under the trade name M-Pyrol and the abbreviations NMP and MePy. It carries no E-code designation and is classified under HS code 29339900.
In pharmaceutical and electronics manufacturing, NMP functions as a carrier solvent that dissolves high-molecular-weight polymers and active compounds through strong dipolar interactions, enabling uniform coating and film formation. In personal care formulations it acts as a humectant and skin conditioner by binding moisture at the stratum corneum level.
NMP is supplied as an industrial-grade liquid meeting REACH registration requirements under EU regulation 1907/2006, where it is subject to authorisation obligations as an SVHC substance. Procurement teams should confirm current authorisation status and supply chain documentation before ordering. Standard packaging includes drums and IBCs for bulk orders.
In pharmaceutical and electronics manufacturing, NMP functions as a carrier solvent that dissolves high-molecular-weight polymers and active compounds through strong dipolar interactions, enabling uniform coating and film formation. In personal care formulations it acts as a humectant and skin conditioner by binding moisture at the stratum corneum level.
NMP is supplied as an industrial-grade liquid meeting REACH registration requirements under EU regulation 1907/2006, where it is subject to authorisation obligations as an SVHC substance. Procurement teams should confirm current authorisation status and supply chain documentation before ordering. Standard packaging includes drums and IBCs for bulk orders.
Physical Properties
| Melting Point | -25 °C |
| Boiling Point | 202 °C @ Press: 760 Torr |
| Density | 1.027 g/cm³ @ Temp: 25 °C |
| Flash Point | 187 °F |
| Appearance | colourless or light yellow liquid with an amine odour |
| Color | ≤20(APHA) |
| Odor | Slight amine odor |
| Form | Liquid |
| Water Solubility | >=10 g/100 mL at 20 ºC |
| Vapor Pressure | 0.29 mm Hg ( 20 °C) |
| Refractive Index | n 20/D 1.479 |
| pH | 8.5-10.0 (100g/l, H2O, 20℃) |
| Log P | -0.46 at 25℃ |
Safety & Handling (Learn More)
Danger GHS07 GHS08
H
H227H315H319H335H336H360H361H372H373
P
P203P210P260P261P264P270P271P280P318P319P321P403P405P501P264+P265P302+P352P304+P340P332+P317P337+P317P362+P364P370+P378P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29339900 |
| UN Number | 1268 |
| ADR Class | 3 |
| Packing Group | III |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 1 |
Other Names
N-Methyl-2-pyrrolidoneN-Methylpyrrolidone1-methylpyrrolidin-2-oneMethylpyrrolidoneMethyl pyrrolidoneNMPM-PYROL(R)N-METHYLPYROLIDONE
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Raw Materials
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