n-Methylpiperazine
CAS 109-01-3
EC 203-639-5
Formula C5H12N2
MW 100.16 g/mol
Amines Plastics & PolymersPharmaceuticals & HealthcareBiotechnology & Life SciencesWater Treatment CatalysisCross-linking & CuringPreservation & Biocide
Description
N-Methylpiperazine (CAS 109-01-3, EC 203-639-5), also referred to as 1-Methylpiperazine or NMPRZ, is a cyclic diamine with the molecular formula C5H12N2. It carries no assigned E-code and is classified under HS code 29335995 within the amines category.
In pharmaceutical synthesis, N-Methylpiperazine acts as a building block and catalyst, accelerating reaction rates through its dual basic nitrogen sites. In epoxy and polymer systems, it functions as a crosslinker by reacting with electrophilic sites to form covalent network structures. Water treatment formulations also employ it for its antimicrobial action against bacterial biofilms.
N-Methylpiperazine is supplied as a clear liquid in technical and pharmaceutical grades, with material compliant with REACH registration requirements for European supply. Packaging is available in standard drum and IBC formats suited to industrial procurement volumes. Buyers should confirm grade specification against Ph.Eur. or internal quality standards prior to formulation use.
In pharmaceutical synthesis, N-Methylpiperazine acts as a building block and catalyst, accelerating reaction rates through its dual basic nitrogen sites. In epoxy and polymer systems, it functions as a crosslinker by reacting with electrophilic sites to form covalent network structures. Water treatment formulations also employ it for its antimicrobial action against bacterial biofilms.
N-Methylpiperazine is supplied as a clear liquid in technical and pharmaceutical grades, with material compliant with REACH registration requirements for European supply. Packaging is available in standard drum and IBC formats suited to industrial procurement volumes. Buyers should confirm grade specification against Ph.Eur. or internal quality standards prior to formulation use.
Physical Properties
| Melting Point | -6 °C |
| Boiling Point | 138 °C |
| Density | 0.88607 g/cm³ @ Temp: 40.00 °C |
| Flash Point | 108 °F |
| Appearance | clear liquid |
| Color | Clear |
| Form | Liquid |
| Water Solubility | soluble |
| Vapor Pressure | 12 hPa (20 °C) |
| Refractive Index | n 20/D 1.466(lit.) |
| pH | 11-12 (50g/l, H2O, 20℃) |
| Log P | -0.57 at 25℃ |
Safety & Handling (Learn More)
Danger GHS02 GHS05 GHS06 GHS07
H
H226H312H314H317H318H330H331H332
P
P210P233P240P241P242P243P260P261P264P271P272P280P284P316P317P320P321P363P405P501P264+P265P302+P352P304+P340P333+P317P362+P364P370+P378P403+P233P403+P235P301+P330+P331P302+P361+P354P303+P361+P353P305+P354+P338
Trade & Regulatory
| HS Code | 29335995 |
| UN Number | 2734 |
| ADR Class | 8 |
| Packing Group | II |
| Storage Class | 3 - Flammable liquids |
| WGK (Germany) | 2 |
Other Names
1-methylpiperazineNMPNMPRZmethylpiperazine1-methyl-piperazinMETHYLPIPERAZINE-N
Related Products
Raw Materials
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