N,N'-Dicyclohexylcarbodiimide
CAS 538-75-0
EC 208-704-1
Formula C13H22N2
MW 206.33 g/mol
Catalysts & Catalyst Precursors Pharmaceuticals & HealthcarePersonal Care & CosmeticsFood & Nutrition CatalysisFlavoring & Acidulant
Description
N,N'-Dicyclohexylcarbodiimide (DCC, also abbreviated DCCI or DCCD, CAS 538-75-0) is a carbodiimide reagent supplied as a waxy crystalline solid. It carries no assigned E-code. It is classified under HS code 29251900 within the Catalysts and Catalyst Precursors category.
DCC functions as a coupling agent by activating carboxylic acids toward nucleophilic attack, enabling amide and ester bond formation under mild conditions. In pharmaceutical synthesis it drives peptide coupling steps where direct condensation is not feasible. In flavour and fragrance manufacturing it facilitates esterification reactions to produce specific aroma compounds with controlled selectivity.
DCC is available in reagent and technical grades to meet the requirements of pharmaceutical and food-grade production workflows. Suppliers operating under REACH registration can provide material with full SDS documentation and batch-level certificates of analysis. Packaging is typically offered in quantities suited to laboratory through to pilot-scale procurement.
DCC functions as a coupling agent by activating carboxylic acids toward nucleophilic attack, enabling amide and ester bond formation under mild conditions. In pharmaceutical synthesis it drives peptide coupling steps where direct condensation is not feasible. In flavour and fragrance manufacturing it facilitates esterification reactions to produce specific aroma compounds with controlled selectivity.
DCC is available in reagent and technical grades to meet the requirements of pharmaceutical and food-grade production workflows. Suppliers operating under REACH registration can provide material with full SDS documentation and batch-level certificates of analysis. Packaging is typically offered in quantities suited to laboratory through to pilot-scale procurement.
Physical Properties
| Melting Point | 34.5 °C |
| Boiling Point | 112 °C @ Press: 3.5 Torr |
| Density | 1.247 g/mL at 25 °C |
| Flash Point | 190 °F |
| Appearance | N,N0 -Dicyclohexylcarbodiimide (DCC) is a white crystalline solid. Odor is sweet and heavy. |
| Color | White to pale yellow |
| Form | Waxy Solid or Crystalline Mass |
| Water Solubility | Reaction |
| Vapor Pressure | 1.044-1.15Pa at 20-25℃ |
| Refractive Index | n 20/D 1.48 |
| Log P | 5.567-6.83 at 25℃ |
Safety & Handling (Learn More)
Danger GHS05 GHS06 GHS07 GHS09 GHS08
H
H302H311H315H317H318H330H371H400H410H413
P
P260P261P262P264P270P271P272P273P280P284P316P317P320P321P330P391P405P501P264+P265P301+P317P302+P352P304+P340P308+P316P332+P317P333+P317P361+P364P362+P364P403+P233P305+P354+P338
Trade & Regulatory
| HS Code | 29251900 |
| UN Number | 2922 |
| ADR Class | 8 |
| Packing Group | II |
| Storage Class | 6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects |
| WGK (Germany) | 3 |
Other Names
N,N'-dicyclohexylmethanediiminedicyclohexylcarbodiimideDCCDCCDDCCICarbodiimide, dicyclohexyl-Bis(cyclohexyl)carbodiimide
Related Products
Raw Materials
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