SoleChem

N,N'-Dicyclohexylcarbodiimide

CAS 538-75-0
EC 208-704-1
Formula C13H22N2
MW 206.33 g/mol
Catalysts & Catalyst Precursors Pharmaceuticals & HealthcarePersonal Care & CosmeticsFood & Nutrition CatalysisFlavoring & Acidulant

Description

N,N'-Dicyclohexylcarbodiimide (DCC, also abbreviated DCCI or DCCD, CAS 538-75-0) is a carbodiimide reagent supplied as a waxy crystalline solid. It carries no assigned E-code. It is classified under HS code 29251900 within the Catalysts and Catalyst Precursors category.

DCC functions as a coupling agent by activating carboxylic acids toward nucleophilic attack, enabling amide and ester bond formation under mild conditions. In pharmaceutical synthesis it drives peptide coupling steps where direct condensation is not feasible. In flavour and fragrance manufacturing it facilitates esterification reactions to produce specific aroma compounds with controlled selectivity.

DCC is available in reagent and technical grades to meet the requirements of pharmaceutical and food-grade production workflows. Suppliers operating under REACH registration can provide material with full SDS documentation and batch-level certificates of analysis. Packaging is typically offered in quantities suited to laboratory through to pilot-scale procurement.

Physical Properties

Melting Point 34.5 °C
Boiling Point 112 °C @ Press: 3.5 Torr
Density 1.247 g/mL at 25 °C
Flash Point 190 °F
Appearance N,N0 -Dicyclohexylcarbodiimide (DCC) is a white crystalline solid. Odor is sweet and heavy.
Color White to pale yellow
Form Waxy Solid or Crystalline Mass
Water Solubility Reaction
Vapor Pressure 1.044-1.15Pa at 20-25℃
Refractive Index n 20/D 1.48
Log P 5.567-6.83 at 25℃

Safety & Handling (Learn More)

Danger GHS05 GHS06 GHS07 GHS09 GHS08
H
H302H311H315H317H318H330H371H400H410H413
P
P260P261P262P264P270P271P272P273P280P284P316P317P320P321P330P391P405P501P264+P265P301+P317P302+P352P304+P340P308+P316P332+P317P333+P317P361+P364P362+P364P403+P233P305+P354+P338

Trade & Regulatory

HS Code 29251900
UN Number 2922
ADR Class 8
Packing Group II
Storage Class 6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects
WGK (Germany) 3

Other Names

N,N'-dicyclohexylmethanediiminedicyclohexylcarbodiimideDCCDCCDDCCICarbodiimide, dicyclohexyl-Bis(cyclohexyl)carbodiimide

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