N,N,N',N'-Tetramethyl-1,6-hexanediamine

N,N,N',N'-Tetramethyl-1,6-hexanediamine (CAS 111-18-2), commonly abbreviated as TMHDA or TMHD and marketed under the trade name LUPRAGEN N 500, is a symmetrical aliphatic diamine with two tertiary amine groups. It carries no assigned E-code. The compound is registered under REACH and classified within HS code 29212900.

In polyurethane manufacturing, TMHDA functions as a tertiary amine catalyst, accelerating the urethane and urea reaction between isocyanates and polyols without incorporating into the polymer backbone. In epoxy and rubber systems, its bifunctional amine structure enables covalent cross-linking, building network density and improving mechanical resistance. It also serves as a pH buffer and conditioning agent in personal care formulations.

TMHDA is supplied as a liquid in standard industrial packaging including drums and IBC containers. It is subject to REACH registration requirements for EU supply. Buyers should confirm grade specifications and SDS documentation to meet application-specific quality standards in polymer, cosmetic, or food-contact contexts.