N,N,N′,N′-Tetramethylethylenediamine
CAS 110-18-9
EC 203-744-6
Formula C6H16N2
MW 116.2 g/mol
Amines Plastics & PolymersFood & NutritionPharmaceuticals & HealthcareBiotechnology & Life Sciences pH Regulation & BufferingCatalysisPreservation & BiocideFlavoring & Acidulant
Description
N,N,N′,N′-Tetramethylethylenediamine, commonly known as TEMED or 1,2-Bis(dimethylamino)ethane, is a tertiary diamine supplied as a colorless to slightly yellow liquid under CAS 110-18-9. It carries no assigned E-code and is catalogued under EC 203-744-6 with HS code 29212900.
In polyacrylamide gel electrophoresis, TEMED accelerates free-radical polymerization by catalyzing the decomposition of ammonium persulfate, enabling controlled gel formation in biotechnology workflows. It also functions as a catalyst in polyurethane synthesis and serves as a pH buffer and antimicrobial agent in select pharmaceutical and food-grade formulations.
TEMED is available in reagent, technical, and food-contact grades, with high-purity lots meeting FCC and Ph.Eur. specifications where applicable. The substance is registered under REACH and requires an up-to-date SDS for EU trade. Packaging typically ranges from laboratory quantities to bulk drums for industrial procurement.
In polyacrylamide gel electrophoresis, TEMED accelerates free-radical polymerization by catalyzing the decomposition of ammonium persulfate, enabling controlled gel formation in biotechnology workflows. It also functions as a catalyst in polyurethane synthesis and serves as a pH buffer and antimicrobial agent in select pharmaceutical and food-grade formulations.
TEMED is available in reagent, technical, and food-contact grades, with high-purity lots meeting FCC and Ph.Eur. specifications where applicable. The substance is registered under REACH and requires an up-to-date SDS for EU trade. Packaging typically ranges from laboratory quantities to bulk drums for industrial procurement.
Physical Properties
| Melting Point | -55 °C |
| Boiling Point | 121 °C |
| Density | 0.7765 g/cm³ @ Temp: 20 °C |
| Flash Point | 50 °F |
| Appearance | Colorless to slightly yellow liquid |
| Color | Clear colorless to slightly yellow |
| Odor | Amine like |
| Form | Liquid |
| Water Solubility | miscible |
| Vapor Pressure | 21 hPa (20 °C) |
| Refractive Index | n 20/D 1.4179(lit.) |
| pH | 8.0-8.5 (0.1g/l, H2O, 20℃) |
| Log P | -0.13 at 20.2℃ |
Safety & Handling (Learn More)
Danger GHS02 GHS05 GHS07 GHS06 GHS09 GHS08
H
H225H302H312H314H318H331H332H370H411H302+H332
P
P210P233P240P241P242P243P260P261P264P270P271P273P280P316P317P321P330P363P391P405P501P264+P265P301+P317P302+P352P304+P340P308+P316P362+P364P370+P378P403+P233P403+P235P301+P330+P331P302+P361+P354P303+P361+P353P305+P354+P338
Trade & Regulatory
| HS Code | 29212900 |
| UN Number | 2372 |
| ADR Class | 3 |
| Packing Group | II |
| Storage Class | 3 - Flammable liquids |
| WGK (Germany) | 1 |
Other Names
TetramethylethylenediamineN,N,N',N'-tetramethylethane-1,2-diamineTMEDAN,N,N',N'-tetramethylethylenediamineTEMED1,4-DIAMINOBUTANEBIS(DIMETHYLAMINO)ETHANE1,2-DI(DIMETHYLAMINO)ETHANE1,2-Bis(dimethylamino)ethane
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