Norfloxacin
CAS 70458-96-7
EC 274-614-4
Formula C16H18FN3O3
MW 409.41 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & Cosmetics Preservation & Biocide
Description
Norfloxacin (CAS 70458-96-7, EC 274-614-4) is a synthetic fluoroquinolone antibacterial compound, also known under trade names Noroxin and development codes AM 715, MK-366, and MK 0366. It carries no assigned E-code. It belongs to the pharmaceutical intermediates category with the molecular formula C16H18FN3O3.
In pharmaceutical manufacturing, norfloxacin serves as an active antibacterial agent targeting gram-negative and gram-positive bacteria by inhibiting DNA gyrase and topoisomerase IV, disrupting bacterial replication. In personal care formulations, it functions as an antimicrobial and skin-protective agent, providing preservation activity against microbial contamination in topical products.
Norfloxacin is supplied as a crystalline powder grade compliant with Ph.Eur. specifications and subject to REACH registration requirements within the EU. Procurement quantities are available for industrial-scale formulation under HS code 29335900. Buyers should confirm current regulatory status for intended application prior to ordering.
In pharmaceutical manufacturing, norfloxacin serves as an active antibacterial agent targeting gram-negative and gram-positive bacteria by inhibiting DNA gyrase and topoisomerase IV, disrupting bacterial replication. In personal care formulations, it functions as an antimicrobial and skin-protective agent, providing preservation activity against microbial contamination in topical products.
Norfloxacin is supplied as a crystalline powder grade compliant with Ph.Eur. specifications and subject to REACH registration requirements within the EU. Procurement quantities are available for industrial-scale formulation under HS code 29335900. Buyers should confirm current regulatory status for intended application prior to ordering.
Physical Properties
| Melting Point | 227-228 °C |
| Boiling Point | 555.8±50.0 °C(Predicted) |
| Density | 1.2504 (estimate) |
| Appearance | Off-white to light yellow cryst powder |
| Color | White to yellow |
| Form | Crystalline Powder |
| Water Solubility | Soluble in acetic acid. Also soluble in acetone or cloroform. Slightly soluble in water |
Safety & Handling (Learn More)
Danger GHS05 GHS07 GHS08
H
H318H319H361
P
P203P280P317P318P405P501P264+P265P337+P317P305+P351+P338P305+P354+P338
Trade & Regulatory
| HS Code | 29335900 |
| WGK (Germany) | 2 |
Other Names
NFLXMK-366Noroxin4803PAM 715Mk 0366baccidalchibroxin
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Raw Materials
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