o-Phthalic acid
CAS 88-99-3
EC 201-873-2
Formula C8H6O4
MW 166.13 g/mol
Organic Acids Personal Care & CosmeticsFood & NutritionPharmaceuticals & Healthcare Preservation & BiocideCatalysispH Regulation & Buffering
Description
O-Phthalic Acid (CAS 88-99-3) is a benzene dicarboxylic acid commercially available under trade names including Sunftal 20 and HA 21, and referenced in chemical databases as NSC 5348 and M 2. It carries no assigned E-code and is classified under EC 201-873-2.
In pharmaceutical formulations, O-Phthalic Acid functions as a pH buffer and catalyst in esterification reactions, enabling controlled synthesis of excipients and active intermediates. In personal care products, it acts as a preservative and skin conditioner by disrupting microbial membrane integrity, extending product shelf life without relying on halogenated compounds.
The material is supplied as a white crystalline powder meeting Ph.Eur. and FCC grade specifications, with REACH compliance documentation available. It is classified under HS code 29173980 and typically offered in 25 kg bags or bulk quantities, with safety data sheets aligned to EU GHS requirements.
In pharmaceutical formulations, O-Phthalic Acid functions as a pH buffer and catalyst in esterification reactions, enabling controlled synthesis of excipients and active intermediates. In personal care products, it acts as a preservative and skin conditioner by disrupting microbial membrane integrity, extending product shelf life without relying on halogenated compounds.
The material is supplied as a white crystalline powder meeting Ph.Eur. and FCC grade specifications, with REACH compliance documentation available. It is classified under HS code 29173980 and typically offered in 25 kg bags or bulk quantities, with safety data sheets aligned to EU GHS requirements.
Physical Properties
| Melting Point | 191 °C (decomp) |
| Boiling Point | 214.32°C (rough estimate) |
| Density | 1.593 g/cm³ @ Temp: 15 °C |
| Flash Point | 168 °C |
| Appearance | white crystals |
| Color | White |
| Form | Powder |
| Water Solubility | 7 g/L (25 ºC) |
| Vapor Pressure | 7.8 hPa (191 °C) |
| Refractive Index | 1.5100 (estimate) |
| pH | 2 (5g/l, H2O, 20℃) |
| Log P | 0.73 at 20℃ |
Safety & Handling (Learn More)
Danger GHS08 GHS05 GHS07
H
H315H318H319H335
P
P203P261P264P271P280P317P318P319P321P405P501P264+P265P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338P305+P354+P338
Trade & Regulatory
| HS Code | 29173980 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 1 |
Other Names
Phthalic acidPhthalinateM 2HA 21Sunftal 20Pathalic acido-Dicarboxybenzene
Related Products
Raw Materials
Derivatives
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