Octenidine dihydrochloride

Octenidine dihydrochloride (CAS 70775-75-6) is a bis-pyridinium compound used as an antimicrobial active, commercially known under trade names including Neo Kodan, Octenilin, Octenidol, and Octeniderm. It carries no assigned E-code and is classified under the amines category with HS code 2933399990.

In pharmaceutical wound care and skin antisepsis, octenidine dihydrochloride disrupts bacterial and fungal cell membranes by binding to negatively charged phospholipid bilayers, achieving broad-spectrum activity at low concentrations. In personal care preservation systems, it functions as a primary biocide in rinse-off and leave-on formulations where traditional preservatives face regulatory or tolerance constraints.

The material is supplied as a solid and is subject to REACH registration requirements within the EU. Procurement teams should verify compliance with Ph.Eur. monograph specifications where pharmaceutical-grade material is required. Suppliers typically offer this substance in laboratory and commercial quantities; buyers should confirm grade, purity certificate, and packaging format at inquiry.