p-Synephrine
CAS 94-07-5
EC 202-300-9
Formula C9H13NO2
MW 167.21 g/mol
Pharmaceutical Intermediates Personal Care & CosmeticsPharmaceuticals & Healthcare Preservation & Biocide
Description
p-Synephrine (CAS 94-07-5) is a naturally occurring alkaloid found in bitter orange (Citrus aurantium) extract, commercially known under the names Sympatol, Oxedrine, Simpalon, and Analeptin. It carries no assigned E-code and is classified as a pharmaceutical intermediate with adrenergic activity.
In personal care formulations, p-Synephrine functions as a skin conditioner and antimicrobial agent, acting on adrenergic receptors to influence skin tone and microbial membrane integrity. It is also investigated as a colorant precursor in cosmetic applications and serves as an active pharmaceutical intermediate in sympathomimetic drug synthesis.
This material is supplied as a pharmaceutical-grade powder compliant with REACH registration requirements. Procurement teams should confirm applicable Ph.Eur. or in-house specification alignment prior to ordering. Standard packaging formats for B2B supply are available on request, and the product is classified under HS code 29225000 for import and export documentation.
In personal care formulations, p-Synephrine functions as a skin conditioner and antimicrobial agent, acting on adrenergic receptors to influence skin tone and microbial membrane integrity. It is also investigated as a colorant precursor in cosmetic applications and serves as an active pharmaceutical intermediate in sympathomimetic drug synthesis.
This material is supplied as a pharmaceutical-grade powder compliant with REACH registration requirements. Procurement teams should confirm applicable Ph.Eur. or in-house specification alignment prior to ordering. Standard packaging formats for B2B supply are available on request, and the product is classified under HS code 29225000 for import and export documentation.
Physical Properties
| Melting Point | 184.5 °C |
| Boiling Point | 341.1 °C @ Press: 760 Torr |
| Density | 1.1222 (rough estimate) |
| Appearance | Off-White to Beige Powder |
| Color | White to Off-White |
| Form | neat |
| Refractive Index | 1.4680 (estimate) |
| Log P | -0.450 |
Safety & Handling (Learn More)
Warning GHS07
H
H315H319H335
P
P261P264P271P280P319P321P405P501P264+P265P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29225000 |
| WGK (Germany) | 3 |
Other Names
4-[1-hydroxy-2-(methylamino)ethyl]phenolSympatolOxedrineSimpalonAnaleptinSynephrineSYNEPHERINE
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Raw Materials
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