Palladium(ii) acetate

Palladium(II) Acetate, CAS 3375-31-3, is an organopalladium coordination compound also known as Palladium Diacetate, Diacetoxypalladium, and Palladous Acetate. It carries no assigned E-code and is catalogued under EC 222-164-4. It functions primarily as a catalyst precursor, activating under mild conditions to generate reactive palladium(0) species in situ.

In pharmaceutical synthesis, it drives cross-coupling reactions such as Heck, Suzuki, and Buchwald-Hartwig transformations, forming carbon-carbon and carbon-heteroatom bonds that are otherwise difficult to achieve. In personal care formulations, it acts as an antimicrobial agent and surface modifier, interacting with biological membranes to inhibit microbial growth at low concentrations.

Palladium(II) Acetate is supplied in powder, flake, and crystalline forms to suit laboratory and industrial-scale processes. It is subject to REACH registration requirements within the EU and is classified under HS code 28439090. Procurement teams should confirm purity specifications and packaging formats directly with the supplier.