Pinacolborane

Pinacolborane (PINB, CAS 25015-63-8, EC 607-485-3) is a boron-hydrogen reagent derived from pinacol and borane. Also referred to as pinacolboronane or pinacolatoborane, it carries no assigned E-code and is classified under HS code 29209090 as a pharmaceutical intermediate.

In pharmaceutical synthesis, PINB serves as a selective hydroboration agent, delivering boron to unsaturated substrates to produce pinacol boronate esters used directly in Miyaura and Suzuki-Miyaura cross-coupling reactions. In biotechnology and specialty cleaning formulations, it functions as a catalyst activator and polymerization initiator, enabling controlled chain-growth processes under mild conditions.

PINB is supplied as a clear colorless liquid compliant with REACH registration requirements. It is handled under standard inert-atmosphere protocols given its moisture sensitivity. Procurement teams should confirm purity grade specifications and packaging configurations, typically available in sealed metal containers or glass ampules, directly with our technical sales team.