Piperazine
CAS 110-85-0
EC 203-808-3
Formula C4H10N2
MW 86.14 g/mol
Amines Plastics & PolymersPharmaceuticals & Healthcare Cross-linking & CuringCatalysis
Description
Piperazine (CAS 110-85-0) is a cyclic diamine supplied as crystalline flakes, also known under trade names including Antepan, Antiren, Dispermine, and Lumbrical. It carries no assigned E-code and is classified under the amines category with EC number 203-808-3 and formula C4H10N2.
In plastics and polymer manufacturing, piperazine functions as a crosslinker by reacting with epoxy or isocyanate groups to form covalent network structures that improve mechanical and thermal performance. In pharmaceutical synthesis and agrochemical production, it serves as a catalyst and key building block, accelerating reaction pathways through its dual secondary amine sites.
Piperazine is available in pharmaceutical-grade forms compliant with Ph.Eur. standards and in technical grades for industrial applications, both subject to REACH registration requirements. Standard packaging includes multi-layer bags and fiber drums. Procurement teams should confirm grade specification against intended application prior to ordering.
In plastics and polymer manufacturing, piperazine functions as a crosslinker by reacting with epoxy or isocyanate groups to form covalent network structures that improve mechanical and thermal performance. In pharmaceutical synthesis and agrochemical production, it serves as a catalyst and key building block, accelerating reaction pathways through its dual secondary amine sites.
Piperazine is available in pharmaceutical-grade forms compliant with Ph.Eur. standards and in technical grades for industrial applications, both subject to REACH registration requirements. Standard packaging includes multi-layer bags and fiber drums. Procurement teams should confirm grade specification against intended application prior to ordering.
Physical Properties
| Melting Point | 106 °C |
| Boiling Point | 146 °C @ Press: 760 Torr |
| Density | 1.1 g/cm³ |
| Flash Point | 65 °C |
| Appearance | Solid |
| Color | White to slightly yellow |
| Odor | at 0.10 % in dipropylene glycol. ammoniacal |
| Form | Crystalline Flakes |
| Water Solubility | 150 g/L (20 ºC) |
| Vapor Pressure | 0.8 mm Hg ( 20 °C) |
| Refractive Index | 1.4460 |
| pH | 11.0-12.5 (25℃, 0.1M in H2O) |
| Log P | -1.24 at 20-25℃ |
Safety & Handling (Learn More)
Danger GHS05 GHS08 GHS02 GHS07
H
H228H302H312H314H317H318H332H334H335H361H370H371H372H373H402
P
P203P210P233P240P241P260P261P264P270P271P272P273P280P284P316P317P318P319P321P330P363P403P405P501P264+P265P301+P317P302+P352P304+P340P308+P316P333+P317P342+P316P362+P364P370+P378P403+P233P301+P330+P331P302+P361+P354P305+P354+P338
Trade & Regulatory
| HS Code | 29335900 |
| UN Number | 2579 |
| ADR Class | 8 |
| Packing Group | III |
| Storage Class | 4.1B - Flammable solid hazardous materials |
| WGK (Germany) | 1 |
Other Names
PiperazinAntirenAntepanLumbricalDisperminePiperazidine1,4-PiperazineHexahydropyrazine
Related Products
Raw Materials
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