SoleChem

Piperazine

CAS 110-85-0
EC 203-808-3
Formula C4H10N2
MW 86.14 g/mol
Amines Plastics & PolymersPharmaceuticals & Healthcare Cross-linking & CuringCatalysis

Description

Piperazine (CAS 110-85-0) is a cyclic diamine supplied as crystalline flakes, also known under trade names including Antepan, Antiren, Dispermine, and Lumbrical. It carries no assigned E-code and is classified under the amines category with EC number 203-808-3 and formula C4H10N2.

In plastics and polymer manufacturing, piperazine functions as a crosslinker by reacting with epoxy or isocyanate groups to form covalent network structures that improve mechanical and thermal performance. In pharmaceutical synthesis and agrochemical production, it serves as a catalyst and key building block, accelerating reaction pathways through its dual secondary amine sites.

Piperazine is available in pharmaceutical-grade forms compliant with Ph.Eur. standards and in technical grades for industrial applications, both subject to REACH registration requirements. Standard packaging includes multi-layer bags and fiber drums. Procurement teams should confirm grade specification against intended application prior to ordering.

Physical Properties

Melting Point 106 °C
Boiling Point 146 °C @ Press: 760 Torr
Density 1.1 g/cm³
Flash Point 65 °C
Appearance Solid
Color White to slightly yellow
Odor at 0.10 % in dipropylene glycol. ammoniacal
Form Crystalline Flakes
Water Solubility 150 g/L (20 ºC)
Vapor Pressure 0.8 mm Hg ( 20 °C)
Refractive Index 1.4460
pH 11.0-12.5 (25℃, 0.1M in H2O)
Log P -1.24 at 20-25℃

Safety & Handling (Learn More)

Danger GHS05 GHS08 GHS02 GHS07
H
H228H302H312H314H317H318H332H334H335H361H370H371H372H373H402
P
P203P210P233P240P241P260P261P264P270P271P272P273P280P284P316P317P318P319P321P330P363P403P405P501P264+P265P301+P317P302+P352P304+P340P308+P316P333+P317P342+P316P362+P364P370+P378P403+P233P301+P330+P331P302+P361+P354P305+P354+P338

Trade & Regulatory

HS Code 29335900
UN Number 2579
ADR Class 8
Packing Group III
Storage Class 4.1B - Flammable solid hazardous materials
WGK (Germany) 1

Other Names

PiperazinAntirenAntepanLumbricalDisperminePiperazidine1,4-PiperazineHexahydropyrazine

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