Pregabalin
CAS 148553-50-8
EC 604-639-1
Formula C8H17NO2
MW 159.23 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & CosmeticsFood & Nutrition Humectant & MoisturizingFlavoring & AcidulantpH Regulation & Buffering
Description
Pregabalin (CAS 148553-50-8, EC 604-639-1, formula C8H17NO2) is a gamma-aminobutyric acid analogue developed under the trade names Lyrica and CI-1008, also referenced as PD 144723. It carries no assigned E-code and is classified within pharmaceutical intermediates.
In pharmaceutical manufacturing, pregabalin acts on voltage-gated calcium channels to modulate neurotransmitter release, making it a key active substance in analgesic and anticonvulsant drug formulations. In personal care applications, it functions as a humectant and skin conditioner by attracting and retaining moisture within the formulation matrix.
Pregabalin is supplied as an off-white powder meeting Ph.Eur. and ICH quality standards, with REACH compliance documentation available upon request. It is classified under HS code 29224900. Procurement teams should confirm controlled substance status under national regulations before ordering, as scheduling varies across EU member states.
In pharmaceutical manufacturing, pregabalin acts on voltage-gated calcium channels to modulate neurotransmitter release, making it a key active substance in analgesic and anticonvulsant drug formulations. In personal care applications, it functions as a humectant and skin conditioner by attracting and retaining moisture within the formulation matrix.
Pregabalin is supplied as an off-white powder meeting Ph.Eur. and ICH quality standards, with REACH compliance documentation available upon request. It is classified under HS code 29224900. Procurement teams should confirm controlled substance status under national regulations before ordering, as scheduling varies across EU member states.
Physical Properties
| Melting Point | 266-268 °C |
| Boiling Point | 274.0±23.0 °C(Predicted) |
| Density | 0.444 g/cm³ (bulk) |
| Flash Point | 9°C |
| Appearance | Off-White Solid |
| Color | white to beige |
| Form | white powder |
| Water Solubility | Soluble to 100 mM in water |
Safety & Handling (Learn More)
Danger GHS05 GHS08
H
H318H361H373
P
P203P260P280P317P318P319P405P501P264+P265P305+P354+P338
Trade & Regulatory
| HS Code | 29224900 |
| UN Number | 1230 |
| Packing Group | II |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
(3S)-3-(aminomethyl)-5-methylhexanoic acidLyrica®LyricaCI 1008PregablinPD 144723(R)-Pregabalin(S)-Pregabalin
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