SoleChem

Pyrrolidinyl diaminopyrimidine oxide

CAS 55921-65-8
EC 611-333-1
Formula C8H13N5O
MW 195.22 g/mol
Pharmaceutical Intermediates Personal Care & CosmeticsPharmaceuticals & Healthcare pH Regulation & Buffering

Description

Pyrrolidinyl diaminopyrimidine oxide (CAS 55921-65-8, EC 611-333-1), also known by the trade names Nanoxidil and Triaminodil, is a synthetic pyrimidine derivative with the molecular formula C8H13N5O. It carries no assigned E-code and is classified within pharmaceutical intermediates.

In personal care formulations, it is used as an active ingredient in topical scalp treatments where it functions as a potassium channel opener, promoting follicular activity at the dermal level. It also serves as a pH-regulating agent in cosmetic systems, where its buffering capacity helps stabilise formulation pH within target ranges for dermal compatibility.

This material is supplied to REACH-compliant standards for the European market. Procurement teams should confirm applicable cosmetic notification requirements under EU Regulation 1223/2009 prior to formulation. Packaging formats and available grades are confirmed at the time of enquiry based on order volume and end-use application.

Physical Properties

Melting Point 278 °C (decomp)
Boiling Point 549.3±60.0 °C(Predicted)
Density 1.60

Safety & Handling (Learn More)

Warning GHS07
H
H302
P
P264P270P330P501P301+P317

Other Names

3-hydroxy-2-imino-6-pyrrolidin-1-ylpyrimidin-4-amineNanoxidilTriaminodil2,4-Diamino-6-pyrrolidinopyrimidine 3-oxide3-oxy-6-pyrrolidin-1-yl-pyrimidine-2,4-diamine6-(1-Pyrrolidinyl)-2,4-pyrimidinediamine 3-oxide2,6-Diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide

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