(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid
CAS 94050-90-5
EC 407-960-3
Formula C9H10O4
MW 182.17 g/mol
Organic Acids Personal Care & CosmeticsPharmaceuticals & Healthcare Preservation & BiocideAntioxidant & StabilizerUV Protection & Stabilization
Description
(R)-(+)-2-(4-Hydroxyphenoxy)propionic acid, commonly abbreviated as HPPA, is a chiral organic acid with CAS number 94050-90-5 and EC number 407-960-3. It carries no assigned E-code. The compound belongs to the phenoxypropionic acid family and is handled as a solid at standard conditions.
In personal care formulations, HPPA functions as a skin conditioner and protectant by interacting with epidermal proteins to support barrier integrity. Its phenolic hydroxyl group provides antioxidant activity by scavenging free radicals, while its UV-absorbing capacity helps stabilize light-sensitive formulations. Pharmaceutical applications leverage these same mechanisms for protective and preservative purposes in topical preparations.
HPPA is supplied in solid form and falls under REACH registration requirements for European market compliance. Procurement should reference HS code 29189900 for customs classification. Buyers should confirm grade specifications and batch documentation directly with the supplier to meet cosmetic or pharmaceutical quality standards.
In personal care formulations, HPPA functions as a skin conditioner and protectant by interacting with epidermal proteins to support barrier integrity. Its phenolic hydroxyl group provides antioxidant activity by scavenging free radicals, while its UV-absorbing capacity helps stabilize light-sensitive formulations. Pharmaceutical applications leverage these same mechanisms for protective and preservative purposes in topical preparations.
HPPA is supplied in solid form and falls under REACH registration requirements for European market compliance. Procurement should reference HS code 29189900 for customs classification. Buyers should confirm grade specifications and batch documentation directly with the supplier to meet cosmetic or pharmaceutical quality standards.
Physical Properties
| Melting Point | 145-148 °C (lit.) |
| Boiling Point | 367.5±17.0 °C(Predicted) |
| Density | 1.302±0.06 g/cm3(Predicted) |
| Color | Off-White |
| Form | Solid |
| Refractive Index | 38 ° (C=0.1, MeOH) |
Safety & Handling (Learn More)
Danger GHS05
H
H318
P
P280P317P264+P265P305+P354+P338
Trade & Regulatory
| HS Code | 29189900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 1 |
Other Names
Hydroxyphenoxy Propionic AcidHPPAD-HPPAR-(+)-2-(HYDROXYPHENOXY)PROPIONICD-2-(4-HYDROXYPHENOXY)PROPIONIC ACIDR-2-(4-HYDROXYPHENOXY)PROPANOIC ACID(R)-2-(4-HYDROPHENOXY)PROPIONIC ACID(R)-2-(4-Hydroxyphenoxy)propanoic acid
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