Rabeprazole sodium
CAS 117976-90-6
EC 629-730-3
Formula C18H21N3O3S.Na
MW 381.42 g/mol
Pharmaceutical Intermediates Pharmaceuticals & Healthcare Preservation & Biocide
Description
Rabeprazole sodium (CAS 117976-90-6) is a sodium salt proton pump inhibitor classified under E-code E 3810, also known commercially as Pariet, Aciphex, and Rabicip. It belongs to the benzimidazole class of pharmaceutical compounds and is registered under EC number 629-730-3 with the molecular formula C18H21N3O3S.Na.
In pharmaceutical manufacturing, rabeprazole sodium is used as an active pharmaceutical ingredient in solid oral dosage forms targeting gastric acid suppression, where it irreversibly binds to the H+/K+-ATPase enzyme in gastric parietal cells. Its antimicrobial and preservation properties also support formulation research into combination therapies targeting Helicobacter pylori eradication protocols.
Rabeprazole sodium is supplied as a white crystalline powder in pharmaceutical-grade form, compliant with Ph.Eur. monograph standards and REACH regulations applicable within the EU. It is classified under HS code 2933399090 and is available in controlled packaging formats suited to GMP-compliant pharmaceutical procurement workflows.
In pharmaceutical manufacturing, rabeprazole sodium is used as an active pharmaceutical ingredient in solid oral dosage forms targeting gastric acid suppression, where it irreversibly binds to the H+/K+-ATPase enzyme in gastric parietal cells. Its antimicrobial and preservation properties also support formulation research into combination therapies targeting Helicobacter pylori eradication protocols.
Rabeprazole sodium is supplied as a white crystalline powder in pharmaceutical-grade form, compliant with Ph.Eur. monograph standards and REACH regulations applicable within the EU. It is classified under HS code 2933399090 and is available in controlled packaging formats suited to GMP-compliant pharmaceutical procurement workflows.
Physical Properties
| Melting Point | 140-141 °C (decomp) |
| Appearance | White Crystalline Solid |
| Color | white to beige |
| Form | powder |
| Water Solubility | H2O: 10mg/mL (clear solution) |
Safety & Handling (Learn More)
Warning GHS07 GHS08
H
H302H315H317H319H335H371H413
P
P260P261P264P270P271P272P273P280P319P321P330P405P501P264+P265P301+P317P302+P352P304+P340P308+P316P332+P317P333+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 2933399090 |
| WGK (Germany) | 3 |
Other Names
Sodium rabeprazoleParieE 3810ParietRabicipAciphex
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