Retinol
CAS 68-26-8
EC 200-683-7
Formula C20H30O
MW 286.45 g/mol
Vitamins & Nutrients Personal Care & CosmeticsFood & NutritionPharmaceuticals & Healthcare Antioxidant & StabilizerFlavoring & AcidulantHumectant & Moisturizing
Description
Retinol (CAS 68-26-8) is a fat-soluble vitamin A alcohol, commercially known under trade names including Acon, Afaxin, Anatola, Agiolan, and ATROL. It carries no assigned E-code and is identified under EC number 200-683-7 with molecular formula C20H30O.
In personal care formulations, retinol functions as a skin conditioner and emollient by binding to nuclear receptors that regulate keratinocyte differentiation, making it a functional active in anti-aging and barrier-repair products. In pharmaceutical and nutritional applications, it serves as an antioxidant that scavenges free radicals and supports epithelial tissue maintenance at controlled dosage levels.
Retinol is supplied in pharmaceutical-grade (Ph.Eur.) and food-grade (FCC) specifications, with USP grade available for healthcare applications. The substance is REACH-registered and handled under HS code 29362100. Packaging is typically in light-protected, nitrogen-flushed containers to prevent oxidative degradation during storage and transit.
In personal care formulations, retinol functions as a skin conditioner and emollient by binding to nuclear receptors that regulate keratinocyte differentiation, making it a functional active in anti-aging and barrier-repair products. In pharmaceutical and nutritional applications, it serves as an antioxidant that scavenges free radicals and supports epithelial tissue maintenance at controlled dosage levels.
Retinol is supplied in pharmaceutical-grade (Ph.Eur.) and food-grade (FCC) specifications, with USP grade available for healthcare applications. The substance is REACH-registered and handled under HS code 29362100. Packaging is typically in light-protected, nitrogen-flushed containers to prevent oxidative degradation during storage and transit.
Physical Properties
| Melting Point | 62-64 °C |
| Boiling Point | 137-138 °C @ Press: 1 x 10-6 Torr |
| Density | 0.9933 (rough estimate) |
| Flash Point | -26 °C |
| Appearance | Yellow-Orange Powder |
| Color | yellow to orange |
| Form | crystalline |
| Water Solubility | Practically insoluble inwaterorglycerol; soluble in absolute alcohol,methanol,℃hloroform, ether, fats and oils. |
| Refractive Index | 1.641 |
| pH | 6.5-7.5 (20°C, 100g/L in H2O) |
| Log P | 5.680 |
Safety & Handling (Learn More)
Danger GHS07 GHS08
H
H302H317H319H360H413
P
P203P261P264P270P272P273P280P318P321P330P405P501P264+P265P301+P317P302+P352P333+P317P337+P317P362+P364P305+P351+P338
Trade & Regulatory
| HS Code | 29362100 |
| UN Number | 1208 |
| ADR Class | 3 |
| Packing Group | II |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 3 |
Other Names
Vitamin AATROLAconAfaxinAgiolanAnatolaAlphalinaquasol a
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Raw Materials
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