Riboflavin tetrabutyrate

Riboflavin tetrabutyrate (CAS 752-56-7), also known commercially as Hibon, is the fully esterified butyrate derivative of riboflavin (Vitamin B2). It carries no E-code designation and is distinct from standard riboflavin in its enhanced lipid solubility, making it suitable for fat-based formulation systems.

In pharmaceutical and nutraceutical applications, the butyrate ester functions as a lipophilic prodrug, releasing active riboflavin upon enzymatic hydrolysis in vivo. In animal feed and agricultural formulations, this fat-soluble form enables incorporation into lipid matrices and improves stability against oxidative degradation during processing and storage.

Riboflavin tetrabutyrate is supplied as a solid and is subject to REACH registration requirements for EU market supply. Procurement should confirm compliance with applicable pharmacopoeial standards and food-grade specifications depending on end-use. Standard packaging formats vary by supplier; buyers should request certificates of analysis confirming purity and identity.