Rosuvastatin calcium
CAS 147098-20-2
EC 627-028-1
Formula C22H28FN3O6S.1/2Ca
MW 1001.14 g/mol
Pharmaceutical Intermediates Pharmaceuticals & Healthcare
Description
Rosuvastatin Calcium (CAS 147098-20-2) is a calcium salt form of rosuvastatin, a synthetic HMG-CoA reductase inhibitor belonging to the statin class. It is commercially recognised under trade names including Crestor, Rostar, and Fortius, and carries the development code S-4522. No E-code designation applies to this substance.
In pharmaceutical manufacturing, rosuvastatin calcium serves as the active pharmaceutical ingredient in finished-dose formulations targeting hypercholesterolaemia and mixed dyslipidaemia. It functions by competitively inhibiting HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol biosynthesis, thereby reducing LDL-C and triglyceride levels. It is also used as a reference standard in analytical method development and bioequivalence studies.
This material is supplied as a pharmaceutical-grade powder compliant with Ph.Eur. and USP monograph specifications, and is subject to REACH registration requirements within the EU. It is classified under HS code 29350090. Packaging is available in quantities suited to development and commercial-scale procurement.
In pharmaceutical manufacturing, rosuvastatin calcium serves as the active pharmaceutical ingredient in finished-dose formulations targeting hypercholesterolaemia and mixed dyslipidaemia. It functions by competitively inhibiting HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol biosynthesis, thereby reducing LDL-C and triglyceride levels. It is also used as a reference standard in analytical method development and bioequivalence studies.
This material is supplied as a pharmaceutical-grade powder compliant with Ph.Eur. and USP monograph specifications, and is subject to REACH registration requirements within the EU. It is classified under HS code 29350090. Packaging is available in quantities suited to development and commercial-scale procurement.
Physical Properties
| Melting Point | 89.9 °C |
| Appearance | White to Off-White Crystalline Solid |
| Color | white to beige |
| Form | powder |
Safety & Handling (Learn More)
Danger GHS08 GHS09
H
H350H360H370H372H410
P
P203P260P264P270P273P280P318P319P321P391P405P501P308+P316
Trade & Regulatory
| HS Code | 29350090 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
ZD 4522S 4522RostarCRESTORFortiusROSUVASTATIN CA
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