(S)-(+)-Mandelic acid
CAS 17199-29-0
EC 241-240-8
Formula C8H8O3
MW 152.15 g/mol
Organic Acids Personal Care & CosmeticsPharmaceuticals & Healthcare pH Regulation & BufferingPreservation & BiocideAntioxidant & Stabilizer
Description
(S)-(+)-Mandelic acid (CAS 17199-29-0) is the pure S-enantiomer of mandelic acid, also known as L-mandelic acid or amygdalic acid. It carries no assigned E-code and is classified under HS code 29181980. The compound is the chirally resolved form distinguished from racemic mandelic acid by its specific optical rotation.
In pharmaceutical synthesis, (S)-mandelic acid serves as a chiral resolving agent, separating racemic amines into enantiomerically pure intermediates through diastereomeric salt formation. In personal care formulations, it functions as an alpha-hydroxy acid that lowers pH to promote controlled exfoliation and simultaneously acts as an antimicrobial agent by disrupting microbial cell membranes.
This material is supplied as a crystalline powder meeting pharmaceutical-grade specifications aligned with Ph.Eur. standards and is subject to REACH registration requirements for EU import and use. Standard packaging includes 25 kg fibre drums, with smaller quantities available for development-scale procurement.
In pharmaceutical synthesis, (S)-mandelic acid serves as a chiral resolving agent, separating racemic amines into enantiomerically pure intermediates through diastereomeric salt formation. In personal care formulations, it functions as an alpha-hydroxy acid that lowers pH to promote controlled exfoliation and simultaneously acts as an antimicrobial agent by disrupting microbial cell membranes.
This material is supplied as a crystalline powder meeting pharmaceutical-grade specifications aligned with Ph.Eur. standards and is subject to REACH registration requirements for EU import and use. Standard packaging includes 25 kg fibre drums, with smaller quantities available for development-scale procurement.
Physical Properties
| Melting Point | 134 °C |
| Boiling Point | 234.6°C (rough estimate) |
| Density | 1.35 g/cm³ |
| Flash Point | >190°C |
| Appearance | white to light yellow crystal powde |
| Color | White to beige-brown |
| Form | Crystalline Powder |
| Water Solubility | 100 g/L (25 ºC) |
| Refractive Index | 153.5 ° (C=1, H2O) |
| pH | 2.1 (60g/l, H2O, 20℃) |
| Log P | 0.550 (est) |
Safety & Handling (Learn More)
Danger GHS05 GHS07
H
H302H315H318H335
P
P261P264P270P271P280P317P319P321P330P405P501P264+P265P301+P317P302+P352P304+P340P332+P317P362+P364P403+P233P305+P354+P338
Trade & Regulatory
| HS Code | 29181980 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
(2S)-2-hydroxy-2-phenylacetic acidL-Mandelic Acid(S)-mandelic acid(S)-alpha-hydroxybenzeneacetic acidamygdalic acidL-AMYGDALIC ACID(+)-Mandelic acid
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