Sildenafil citrate

Sildenafil citrate (CAS 171599-83-0, EC 638-824-3) is a phosphodiesterase type 5 inhibitor supplied as a pharmaceutical-grade active ingredient. It is recognized under trade names including Viagra and Kamagra, and by the development code UK-92480. No E-code designation applies to this substance.

In pharmaceutical manufacturing, sildenafil citrate is used as the active pharmaceutical ingredient in formulations targeting pulmonary arterial hypertension and erectile dysfunction. It functions by selectively inhibiting PDE5, an enzyme that regulates cyclic GMP degradation in smooth muscle tissue, thereby promoting vasodilation. Research applications also explore its role in cardiovascular and neonatal therapeutic contexts.

Sildenafil citrate is available in pharmaceutical-grade powder form, manufactured in compliance with Ph.Eur. monograph standards and applicable REACH regulations. Procurement quantities typically range from research-scale grams to multi-kilogram batches. Buyers should confirm GMP certification and certificate of analysis documentation prior to sourcing for finished dosage form production.