Silicotungstic acid
CAS 12027-38-2
EC 234-719-8
Formula H.1/4O40SiW12
MW 2896.19 g/mol
Inorganic Acids Pharmaceuticals & Healthcare CatalysispH Regulation & Buffering
Description
Silicotungstic acid (CAS 12027-38-2, EC 234-719-8), also referenced as JM 1493 and α-H4SiW12O40, is a heteropolyacid composed of a silicon-centred tungsten-oxygen cluster. It carries no assigned E-code and belongs to the inorganic acids category. The compound is commercially handled as a crystalline solid hydrate.
In pharmaceutical manufacturing, silicotungstic acid functions as a strong Brønsted acid catalyst, driving condensation and esterification reactions under mild conditions. It is also applied in alkaloid precipitation assays, where it forms insoluble complexes with nitrogen-containing compounds to confirm identity or quantify active substances. Its buffering capacity supports pH control in select synthesis steps.
The material is supplied for industrial and research-grade applications and falls under REACH registration requirements for EU procurement. Buyers should confirm lot-specific documentation including CoA and SDS prior to order. Packaging formats vary by supplier; consult your account contact for available quantities.
In pharmaceutical manufacturing, silicotungstic acid functions as a strong Brønsted acid catalyst, driving condensation and esterification reactions under mild conditions. It is also applied in alkaloid precipitation assays, where it forms insoluble complexes with nitrogen-containing compounds to confirm identity or quantify active substances. Its buffering capacity supports pH control in select synthesis steps.
The material is supplied for industrial and research-grade applications and falls under REACH registration requirements for EU procurement. Buyers should confirm lot-specific documentation including CoA and SDS prior to order. Packaging formats vary by supplier; consult your account contact for available quantities.
Physical Properties
| Melting Point | >300 °C |
| Boiling Point | 210-220 °C @ Press: 1-2 Torr |
| Density | 2.099 g/cm³ |
| Color | White to Off-White |
| Form | Solid |
| Water Solubility | 3015.09g/L at 20℃ |
| Vapor Pressure | 0.024Pa at 25℃ |
Safety & Handling (Learn More)
Danger GHS07 GHS05
H
H290H315H319H335
P
P234P261P264P271P280P319P321P390P405P406P501P264+P265P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| WGK (Germany) | 3 |
Other Names
Tungstosilicic acid hydrateJM 1493tetrahydrogenα-H4SiW12O40*99H2OSilicotungstic aciSilicotungeticacidTUNGSTOSILICIC ACID
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