Sitagliptin phosphate

Sitagliptin phosphate (CAS 654671-78-0), also known by the trade name Januvia and the abbreviations MK-0431 and MK 431, is a pharmaceutical compound with the molecular formula C16H15F6N5O.H3O4P. It belongs to the dipeptidyl peptidase-4 (DPP-4) inhibitor class and is classified as a pharmaceutical intermediate.

In pharmaceutical manufacturing, sitagliptin phosphate serves primarily as an active pharmaceutical ingredient in antidiabetic drug formulations, where it functions by selectively inhibiting the DPP-4 enzyme to regulate blood glucose levels. It is also investigated as a pharmaceutical intermediate in the synthesis of related therapeutic compounds targeting metabolic disorders.

This material is supplied as a white solid suitable for pharmaceutical-grade processing and is expected to meet relevant pharmacopoeial standards applicable to API intermediates. Procurement quantities are available for industrial-scale formulation. Buyers should confirm current REACH registration status and applicable import documentation requirements prior to ordering.