Sulfamethoxazole
CAS 723-46-6
EC 211-963-3
Formula C10H11N3O3S
MW 253.28 g/mol
Pharmaceutical Intermediates Pharmaceuticals & Healthcare
Description
Sulfamethoxazole (CAS 723-46-6, EC 211-963-3) is a sulfonamide-class antibacterial compound, also known by the abbreviations SMZ and trade names including Gantanol, Sinomin, and Urobak. It carries no assigned E-code. It is classified as a pharmaceutical intermediate with the molecular formula C10H11N3O3S.
In pharmaceutical manufacturing, sulfamethoxazole serves as the active starting material or key intermediate in the production of combination antibacterial formulations, most notably paired with trimethoprim. It functions by inhibiting dihydropteroate synthase, blocking bacterial folate synthesis. It is also referenced in colorant and foaming agent research within formulation development contexts.
Sulfamethoxazole is supplied as a neat solid and is available in pharmaceutical-grade specifications aligned with Ph.Eur. monograph requirements. Procurement should confirm REACH registration status for EU import volumes. It is classified under HS code 29350090 for customs purposes.
In pharmaceutical manufacturing, sulfamethoxazole serves as the active starting material or key intermediate in the production of combination antibacterial formulations, most notably paired with trimethoprim. It functions by inhibiting dihydropteroate synthase, blocking bacterial folate synthesis. It is also referenced in colorant and foaming agent research within formulation development contexts.
Sulfamethoxazole is supplied as a neat solid and is available in pharmaceutical-grade specifications aligned with Ph.Eur. monograph requirements. Procurement should confirm REACH registration status for EU import volumes. It is classified under HS code 29350090 for customs purposes.
Physical Properties
| Melting Point | 167 °C |
| Boiling Point | 482°C |
| Density | 1.08 g/cm³ |
| Flash Point | >110°(230°F) |
| Appearance | solid |
| Color | White to Pale Yellow |
| Form | neat |
| Water Solubility | Soluble in ethanol or acetone. Very slightly soluble in water |
| Refractive Index | 1.6630 (estimate) |
Safety & Handling (Learn More)
Warning GHS07 GHS09 GHS08
H
H315H317H319H335H341H350H400H410
P
P203P261P264P271P272P273P280P318P319P321P391P405P501P264+P265P302+P352P304+P340P332+P317P333+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29350090 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 2 |
Other Names
4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamideSMXSMZUrobakMS 53SinominGantanolRo 4-2130
Related Products
Raw Materials
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