Tetrabutylammonium bromide
CAS 1643-19-2
EC 216-699-2
Formula C16H36N.Br
MW 322.37 g/mol
Catalysts & Catalyst Precursors Personal Care & CosmeticsPharmaceuticals & HealthcareFood & Nutrition CatalysisPreservation & BiocideFlavoring & Acidulant
Description
Tetrabutylammonium bromide (TBAB, CAS 1643-19-2) is a quaternary ammonium salt supplied under trade names including Aliquat 100 and Actiron 43-65. It carries no E-code designation. The compound is classified under HS code 29239000 and falls within the broader category of salts and minerals.
In pharmaceutical synthesis, TBAB functions as a phase-transfer catalyst, shuttling anions across aqueous-organic interfaces to accelerate reactions that would otherwise proceed slowly or require harsh conditions. In personal care formulations, its quaternary ammonium structure binds to negatively charged hair surfaces, delivering conditioning performance. It also serves preservation roles in select applications due to its antimicrobial activity against bacteria and fungi.
TBAB is available in crystalline powder form and is subject to REACH registration requirements for EU-based procurement. Buyers should confirm grade suitability against FCC or Ph.Eur. standards depending on the intended application. Standard packaging options vary by supplier; technical and high-purity grades are both commercially available.
In pharmaceutical synthesis, TBAB functions as a phase-transfer catalyst, shuttling anions across aqueous-organic interfaces to accelerate reactions that would otherwise proceed slowly or require harsh conditions. In personal care formulations, its quaternary ammonium structure binds to negatively charged hair surfaces, delivering conditioning performance. It also serves preservation roles in select applications due to its antimicrobial activity against bacteria and fungi.
TBAB is available in crystalline powder form and is subject to REACH registration requirements for EU-based procurement. Buyers should confirm grade suitability against FCC or Ph.Eur. standards depending on the intended application. Standard packaging options vary by supplier; technical and high-purity grades are both commercially available.
Physical Properties
| Melting Point | 100-102 °C |
| Boiling Point | 102 °C |
| Density | 1.039 g/mL at 25 °C |
| Flash Point | 100°C |
| Appearance | white crystals or powder |
| Color | White to slightly cream |
| Odor | Amine like |
| Form | Crystalline Powder |
| Water Solubility | 600 g/L (20 ºC) |
| Vapor Pressure | 0Pa at 25℃ |
| Refractive Index | n20/D 1.422 |
| pH | 3.5 to 7.0 (50 g/L, 25 ℃) |
| Log P | 0.839 at 25℃ |
Safety & Handling (Learn More)
Warning GHS07 GHS08 GHS09
H
H302H315H319H320H335H361H411H412
P
P203P261P264P270P271P273P280P318P319P321P330P391P405P501P264+P265P301+P317P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29239000 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
tetrabutylazanium bromidetetra-N-butylammonium bromideN,N,N-tributyl-1-butanaminium bromideTBABAP 6GIPC-TBA-BRAliquat 100
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