Tetraethylene glycol dimethyl ether
CAS 143-24-8
EC 205-594-7
Formula C10H22O5
MW 222.28 g/mol
Alcohols & Glycols Plastics & PolymersLubricants & MetalworkingBiotechnology & Life SciencesPharmaceuticals & HealthcareElectronics Cross-linking & CuringCatalysisSolvent & CarrierHumectant & MoisturizingPreservation & Biocide
Description
Tetraethylene glycol dimethyl ether (CAS 143-24-8) is an ether-class solvent registered under EC 205-594-7 and commercially available as Tetraglyme, Glyme 5, Ansol E-181, and E 181. It carries the formula C10H22O5 and belongs to the glyme solvent family, characterised by repeating ethylene oxide units capped with methyl groups at both ends.
In polymer processing, Tetraglyme coordinates with metal cations to activate catalytic systems, improving reaction selectivity in polymerisation and cross-linking reactions. In pharmaceutical and biotechnology applications, it functions as a high-boiling carrier solvent that stabilises active compounds during formulation, and its hygroscopic character makes it effective as a humectant in moisture-sensitive processes.
Tetraglyme is supplied under REACH registration and is subject to standard industrial solvent compliance requirements. It is available in technical and high-purity grades, with packaging typically in drums and IBC containers suited to B2B procurement volumes. Buyers should confirm grade specifications against application requirements before ordering.
In polymer processing, Tetraglyme coordinates with metal cations to activate catalytic systems, improving reaction selectivity in polymerisation and cross-linking reactions. In pharmaceutical and biotechnology applications, it functions as a high-boiling carrier solvent that stabilises active compounds during formulation, and its hygroscopic character makes it effective as a humectant in moisture-sensitive processes.
Tetraglyme is supplied under REACH registration and is subject to standard industrial solvent compliance requirements. It is available in technical and high-purity grades, with packaging typically in drums and IBC containers suited to B2B procurement volumes. Buyers should confirm grade specifications against application requirements before ordering.
Physical Properties
| Melting Point | -29.7 °C |
| Boiling Point | 275 °C |
| Density | 1.009 g/cm³ |
| Flash Point | 285 °F |
| Appearance | clear liquid |
| Color | Clear |
| Form | Liquid |
| Water Solubility | Soluble |
| Vapor Pressure | <0.01 mm Hg ( 20 °C) |
| Refractive Index | n 20/D 1.432(lit.) |
| Log P | -0.84 at 23℃ |
Safety & Handling (Learn More)
Danger GHS08 GHS07
H
H336H360
P
P203P261P271P280P318P319P405P501P304+P340P403+P233
Trade & Regulatory
| HS Code | 29091990 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 1 |
Other Names
1-methoxy-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethaneTEGDMETetraglymeGlyme 5Ansol E-181E 181 (ether)Ansul Ether 181ATDIMETHYLTETRAGLYCOL
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