Tetrazole

Tetrazole (CAS 288-94-8, EC 206-023-4, formula CH2N4), also referenced as 1H-Tetrazole, 1H-TZ, and NSC 36712, is a five-membered heterocyclic compound containing four nitrogen atoms. It is classified as a pharmaceutical intermediate and is subject to REACH regulation within the European market.

In pharmaceutical synthesis, tetrazole serves as a bioisostere for carboxylic acid groups, enabling chemists to modify drug candidates for improved metabolic stability and membrane permeability without altering core pharmacological activity. It also functions as a polymerization initiator in specific polymer chemistry workflows, where its thermal decomposition generates reactive nitrogen species that trigger chain reactions.

Tetrazole is available as a white crystalline powder and supplied under REACH-compliant conditions for B2B customers across Europe. It is handled and documented under HS code 29339900. Procurement teams should confirm purity grade requirements and applicable handling classifications prior to ordering, as the compound carries energetic properties relevant to storage and transport compliance.