Theophyline
CAS 58-55-9
EC 200-385-7
Formula C7H8N4O2
MW 180.16 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & Cosmetics pH Regulation & BufferingPreservation & Biocide
Description
Theophylline (CAS 58-55-9) is a methylxanthine compound also known under trade names including Theograd, Elixophyllin, and Theophyllin. It carries no assigned E-code and is classified as a pharmaceutical intermediate with established activity as a bronchodilator and cellular signalling modulator.
In pharmaceutical formulations, theophylline acts as a phosphodiesterase inhibitor, raising intracellular cAMP levels to relax bronchial smooth muscle in respiratory preparations. In personal care applications, it functions as a skin conditioner and pH buffer, and its documented antimicrobial properties contribute to preservation efficacy in topical products.
Theophylline is supplied as a white to light yellow crystalline powder meeting Ph.Eur. monograph specifications, with REACH compliance applicable for EU trade under HS code 29399900. Standard packaging formats for B2B supply include fibre drums and multi-layer bags; pharmaceutical-grade documentation including CoA and safety data sheets is available on request.
In pharmaceutical formulations, theophylline acts as a phosphodiesterase inhibitor, raising intracellular cAMP levels to relax bronchial smooth muscle in respiratory preparations. In personal care applications, it functions as a skin conditioner and pH buffer, and its documented antimicrobial properties contribute to preservation efficacy in topical products.
Theophylline is supplied as a white to light yellow crystalline powder meeting Ph.Eur. monograph specifications, with REACH compliance applicable for EU trade under HS code 29399900. Standard packaging formats for B2B supply include fibre drums and multi-layer bags; pharmaceutical-grade documentation including CoA and safety data sheets is available on request.
Physical Properties
| Melting Point | 270 °C |
| Boiling Point | 312.97°C (rough estimate) |
| Density | 1.51 g/cm³ (crystal) |
| Flash Point | 11 °C |
| Appearance | white to light yellow crystal powder |
| Color | white |
| Form | powder |
| Water Solubility | 8.3 g/L (20 ºC) |
| Refractive Index | 1.6700 (estimate) |
| Log P | -0.020 |
Safety & Handling (Learn More)
Danger GHS08 GHS06 GHS07
H
H301H302H360H361H362H370H372H402
P
P203P260P263P264P270P273P280P318P319P321P330P405P501P301+P316P301+P317P308+P316
Trade & Regulatory
| HS Code | 29399900 |
| UN Number | 2811 |
| ADR Class | 6.1 |
| Packing Group | III |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 1 |
Other Names
1,3-dimethyl-7H-purine-2,6-dionetheophyllinTheophylline1,3-dimethylxanthinetheophylline anhydrousTheogradElixophyllin
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Raw Materials
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