Thymidine 5'-monophosphate
CAS 365-07-1
EC 251-518-0
Formula C10H15N2O8P
MW 366.17 g/mol
Nucleosides & Nucleotides Pharmaceuticals & HealthcareBiotechnology & Life Sciences Polymerization Initiation
Description
Thymidine 5'-monophosphate (CAS 365-07-1), also known as dTMP, 5'-TMP, 5'-thymidylic acid, and deoxythymidylic acid, is a pyrimidine deoxyribonucleotide consisting of the nucleoside thymidine linked to a single phosphate group. It carries no assigned E-code and is classified within the nucleosides and nucleotides category.
In pharmaceutical and biotechnology applications, dTMP serves as a direct precursor in DNA biosynthesis, where it is phosphorylated to dTTP and incorporated into growing DNA strands during polymerization. It is used in cell culture media formulations to support nucleotide salvage pathways and in the production of oligonucleotide-based therapeutics and diagnostic reagents.
Thymidine 5'-monophosphate is supplied at research and manufacturing grades suitable for life science and pharmaceutical use, with material available subject to REACH compliance for European customers. Procurement teams should confirm grade specifications, certificate of analysis requirements, and packaging formats directly with the supplier.
In pharmaceutical and biotechnology applications, dTMP serves as a direct precursor in DNA biosynthesis, where it is phosphorylated to dTTP and incorporated into growing DNA strands during polymerization. It is used in cell culture media formulations to support nucleotide salvage pathways and in the production of oligonucleotide-based therapeutics and diagnostic reagents.
Thymidine 5'-monophosphate is supplied at research and manufacturing grades suitable for life science and pharmaceutical use, with material available subject to REACH compliance for European customers. Procurement teams should confirm grade specifications, certificate of analysis requirements, and packaging formats directly with the supplier.
Trade & Regulatory
| WGK (Germany) | 3 |
Other Names
5'-Thymidylic aciddTMP5′-TMP5′-Thymidylic acidDeoxythymidylic AcidThymidine 5′-phosphateThymidine 5′-monophosphateDeoxythymidine monophosphateThymidine 5′-phosphoric acid
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