Trimethylsilyl triflate
CAS 27607-77-8
EC 248-565-4
Formula C4H9F3O3SSi
MW 222.26 g/mol
Silicones & Silicates Personal Care & Cosmetics Surface Modification & Wetting
Description
Trimethylsilyl triflate (CAS 27607-77-8), also known as TMSOTf or TMS triflate, is a highly reactive silylating agent belonging to the silicones and silicates chemical family. It carries no assigned E-code and is commercially identified under the EC number 248-565-4 with the molecular formula C4H9F3O3SSi.
In personal care formulation, TMSOTf functions as a surface modification agent by transferring a trimethylsilyl group onto hydroxyl-bearing substrates, rendering hair and skin surfaces more hydrophobic. This silylation mechanism underpins its use as both a hair conditioner and skin conditioner ingredient, improving water repellency and tactile feel at the substrate level.
TMSOTf is supplied as a fuming liquid and falls under HS code 29310095 for customs classification within the EU. It is subject to REACH registration requirements. Procurement teams should confirm available pack sizes and storage specifications directly with the supplier, as handling requirements for this reactive material are stringent.
In personal care formulation, TMSOTf functions as a surface modification agent by transferring a trimethylsilyl group onto hydroxyl-bearing substrates, rendering hair and skin surfaces more hydrophobic. This silylation mechanism underpins its use as both a hair conditioner and skin conditioner ingredient, improving water repellency and tactile feel at the substrate level.
TMSOTf is supplied as a fuming liquid and falls under HS code 29310095 for customs classification within the EU. It is subject to REACH registration requirements. Procurement teams should confirm available pack sizes and storage specifications directly with the supplier, as handling requirements for this reactive material are stringent.
Physical Properties
| Melting Point | <25 °C |
| Boiling Point | 140-141 °C |
| Density | 1.225 g/cm³ |
| Flash Point | 78 °F |
| Appearance | clear colourless to light brown fuming liquid |
| Color | Clear colorless to light brown |
| Form | Fuming Liquid |
| Water Solubility | REACTS |
| Vapor Pressure | 4.7 hPa (20 °C) |
| Refractive Index | n 20/D 1.36(lit.) |
Safety & Handling (Learn More)
Danger GHS02 GHS05
H
H226H314
P
P210P233P240P241P242P243P260P264P280P316P321P363P405P501P304+P340P370+P378P403+P235P301+P330+P331P302+P361+P354P303+P361+P353P305+P354+P338
Trade & Regulatory
| HS Code | 29310095 |
| UN Number | 2920 |
| ADR Class | 8 |
| Packing Group | II |
| Storage Class | 3 - Flammable liquids |
| WGK (Germany) | 3 |
Other Names
TMS triflatetrimethylsilyl trifluoromethanesulfonateTMSOTfSILANE TMS-TRIFLATETRIMETHYLSILYL TRIFLUOROMETHYLSULFONATE
Related Products
Need a chemical? Get a quote within 24 hours.