Vardenafil

Vardenafil (CAS 224785-90-4, EC 607-088-5, formula C23H32N6O4S) is a pharmaceutical active ingredient marketed under the trade names Levitra, Vivanza, and Nuviva. It belongs to the class of phosphodiesterase type 5 inhibitors and is classified within pharmaceutical intermediates for regulated manufacturing applications.

In pharmaceutical formulation, vardenafil functions by selectively inhibiting the PDE5 enzyme, modulating cyclic GMP pathways in smooth muscle tissue. It is used as an active pharmaceutical ingredient in solid oral dosage form development and serves as a reference compound in pharmacological research and analytical method validation.

Vardenafil is supplied as a powder conforming to pharmaceutical-grade specifications, with compliance requirements governed by ICH guidelines and applicable Ph.Eur. monograph standards. Procurement should account for REACH registration obligations within the EU. Material is available in research and commercial quantities; documentation including CoA and MSDS is supplied on request.