Rutin

Rutin (CAS No: 153-18-4) Supplier in Europe

Rutin is a powerful flavonoid found in various fruits, vegetables, and plants.

It is known for its antioxidative properties and ability to support cardiovascular health.

By incorporating rutin into one’s diet, individuals may potentially reduce inflammation and strengthen blood vessels, which can aid in maintaining a robust circulatory system.

This natural compound is abundant in foods such as buckwheat, asparagus, and citrus fruits.

Consuming these foods regularly can help ensure an adequate intake of rutin.

Regular consumption can also enhance overall wellness by providing additional health benefits such as improved skin health and a fortified immune system.

Chemical Composition and Properties

Rutin is a bioflavonoid with specific molecular and physicochemical characteristics that make it unique. Understanding these features is essential for comprehending the compound’s potential applications and benefits.

Molecular Structure

Rutin, also known as quercetin-3-rutinoside, has a complex molecular structure.

It comprises quercetin, a flavonol, linked to the disaccharide rutinose. The molecular formula is C₂₇H₃₀O₁₆, with a molecular weight of approximately 610.52 g/mol.

The backbone of rutin is based on a flavonoid structure with multiple hydroxyl groups.

These groups contribute to its antioxidant properties.

The glycosidic bond between the quercetin and rutinose parts is crucial in maintaining its stability and solubility.

Physicochemical Characteristics

Rutin’s physicochemical properties are notable.

It appears as a yellow crystalline powder. It is practically insoluble in cold water but soluble in ethanol and hot water, which impacts its bioavailability.

Another critical property is its melting point, around 190-192°C, a factor in determining its stability during formulation processes.

Additionally, rutin exhibits UV absorption maxima at 257 nm and 355 nm, helping in its identification and quantification in analytical methods.

This compound is stable under standard conditions but can degrade when exposed to extreme UV light or acidic conditions.

This stability is vital for its practical applications in pharmaceuticals and nutraceuticals.

Biological Sources

Rutin is found in a variety of plants, with its occurrence and extraction methods showing clear patterns and preferences. Availability in different species and the techniques to isolate it are essential to understand.

Natural Occurrence

Rutin is predominantly found in fruits and vegetables.

Buckwheat (Fagopyrum esculentum) is one of the richest sources. Additionally, it can be found in citrus fruits, berries, and asparagus.

• Apples: Especially in the peel.
• Tea: Particularly green tea.
• Various herbs: Rooibos and eucalyptus.

These sources ensure that rutin is accessible in common diets, thereby aiding in its ingestion for potential health benefits.

Extraction Methods

Traditional methods to extract rutin involve the use of solvents.

Ethanol extraction is common, which involves soaking plant material in ethanol to dissolve rutin.

Another method is enzyme-assisted extraction, which uses enzymes to break down plant cell walls, releasing rutin.

Modern approaches, like supercritical fluid extraction (SFE), utilize carbon dioxide under high pressure to isolate rutin without using harmful solvents.

This method is gaining popularity due to its efficiency and reduced environmental impact.

Different methods have their pros and cons, affecting purity, yield, and environmental footprint.

Therapeutic Uses

Rutin is known for its potential benefits in managing various vascular and skin conditions. It is particularly noted for its effects on chronic venous insufficiency, hemorrhoidal disease, varicose veins, and skin health.

Chronic Venous Insufficiency

Chronic venous insufficiency (CVI) occurs when veins in the legs do not efficiently return blood to the heart.

Rutin improves venous tone and reduces capillary permeability. This leads to decreased edema and inflammation.

Studies suggest rutin may alleviate symptoms such as pain and heaviness in legs.

Its flavonoid properties help strengthen blood vessel walls, offering symptomatic relief.

It is often recommended in conjunction with compression therapy for optimal results.

Hemorrhoidal Disease

Hemorrhoidal disease involves swollen and inflamed veins in the rectum and anus.

Rutin can reduce bleeding, itching, and discomfort associated with hemorrhoids.

Its anti-inflammatory and vascular-protective properties make it useful in this condition.

Rutin is sometimes prescribed with other treatments like dietary fiber and topical ointments.

Clinical trials have shown promising results in reducing symptoms and improving quality of life for sufferers.

Varicose Veins

Varicose veins are enlarged, twisted veins that often appear in the legs.

Rutin has shown promise in reducing varicose veins’ appearance and related symptoms.

It enhances venous function, promoting better blood flow and reducing vein diameter.

This can help lessen pain, swelling, and the heavy feeling often associated with varicose veins. Regular use can result in significant symptom improvement.

Skin Health

Rutin benefits skin health by protecting against oxidative stress and improving microcirculation.

It helps in maintaining skin elasticity and strength, making it useful in anti-aging treatments.

Its antioxidant properties also aid in reducing the effects of UV exposure and environmental damage.

Topical applications of rutin-enriched formulations can improve overall skin texture and delay signs of aging.

Additionally, rutin might assist in wound healing due to its anti-inflammatory effects.