Hexadecyltrimethylammonium chloride

CAS Number
112-02-7
EC Number
203-928-6
Abbreviation
CTAC

What is Hexadecyltrimethylammonium chloride?

Hexadecyltrimethylammonium chloride (CAS 112-02-7), commonly known as CTAC or cetyltrimethylammonium chloride, is a cationic quaternary ammonium surfactant.

Where is Hexadecyltrimethylammonium chloride used?

  • Hair care: primary conditioning active in rinse-out conditioners, depositing onto damaged hair fiber to reduce static and improve combability
  • Pharmaceuticals: antimicrobial preservative and surface-active agent in topical creams, lotions, and ophthalmic preparations
  • Water treatment: biocidal agent controlling microbial growth in cooling towers and industrial process water
  • Textile finishing: antistatic and softening agent in fabric softeners
  • Its positive charge enables strong adsorption onto negatively charged surfaces, driving use as a conditioning agent, emulsifier, and biocide.

Good to know: Cosmetic grades are subject to purity requirements aligned with PCPC and Ph. Eur. standards.

Commercial specifications

  • Aqueous solution, typically 25–30% active content
  • Cosmetic-grade and technical-grade specifications
  • Packaging: drums to IBC totes for liquid grades; bags for solid forms

Other Names (Synonyms)

Cetyltrimethyl ammonium chloride|Hexadecyl(trimethyl)azanium chloride|Cetrimonium chloride|CTAC

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What are the physical properties of Hexadecyltrimethylammonium chloride?

Melting Point 2 °C
Boiling Point 475.54°C (rough estimate)
Density 0.88 g/cm³ @ Temp: 60 °C
Appearance Liquid
Color White
Odor Bland
Form Amorphous Powder
Water Solubility Soluble
Vapor Pressure 0.006Pa at 25℃
Refractive Index n 20/D 1.3778
pH pH(50g/l, 25℃) : 6.0~8.5
Log P 3.08 at 25℃

How is Hexadecyltrimethylammonium chloride classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS06· Toxic GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H302 Harmful if swallowed
H311 Toxic in contact with skin
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash … thoroughly after handling.

Which trade and regulatory codes apply to Hexadecyltrimethylammonium chloride?

HS Code 29239000
UN Number 3082
ADR Class 9
Packing Group III
WGK (Germany) 3
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