Polyquaternium-51

Polyquaternium-51 (CAS 125275-25-4) is a phospholipid-based cationic polymer designed to mimic the moisture-retention behavior of cell membranes. It delivers durable hydration and surface conditioning in personal care and pharmaceutical formulations.

In skincare and facial care products, it forms a biomimetic film on the skin surface that binds moisture and reduces transepidermal water loss without occlusion. This makes it an essential ingredient for high-end moisturizing serums.

Hair care formulators use it in conditioners and leave-on treatments, where it improves wet combability. It imparts a smooth, substantive feel through electrostatic deposition on damaged hair fibers during the washing process.

Ophthalmic formulations, including contact lens solutions and eye drops, rely on its biocompatibility and surface-wetting properties. These characteristics improve overall comfort and lens lubrication for the end user.

In pharmaceutical topical preparations, it functions as a rheology modifier and surface conditioner. This supports uniform active ingredient distribution across the skin surface for better therapeutic outcomes and absorption.

The material is supplied as an aqueous solution, with active polymer content typically ranging from 30% to 50% depending on the grade. Standard commercial grades correspond to the PMB and Purebright product lines.

The product is available in cosmetic and pharmaceutical quality to meet various regulatory requirements. Packaging is typically in drums or intermediate bulk containers suited to industrial liquid handling and storage.