Dequalinium

Dequalinium (CAS 6707-58-0), commonly dequalinium chloride, is a quaternary ammonium bisquinolinium compound used as an antimicrobial active in pharmaceutical and personal care formulations.

Where is Dequalinium used?

• Pharmaceutical manufacturing: active ingredient in topical antiseptic lozenges
• Throat sprays and oral rinses targeting oropharyngeal infections
• Vaginal tablets and pessaries for bacterial vaginosis and mixed vaginal infections
• Personal care: antiseptic mouthwashes and medicated skin preparations requiring preservative-level antimicrobial activity
• Research and specialty chemicals: mitochondria-targeting agent in experimental drug delivery systems
• It functions as a broad-spectrum biocide effective against bacteria, fungi, and certain protozoa at low concentrations.

Good to know: Standard grades include pharmaceutical-grade material meeting USP, BP, or Ph. Eur. specifications for industrial use.

Commercial specifications

• High-purity grades for API and finished dosage form manufacturing
• Packaging in small quantities for R&D through to kilogram-scale lots for commercial production