Dequalinium

Dequalinium (CAS 6707-58-0), commonly supplied as dequalinium chloride, is a quaternary ammonium bisquinolinium compound used as an antimicrobial active in pharmaceutical and personal care formulations. It functions as a broad-spectrum biocide effective against bacteria, fungi, and certain protozoa at low concentrations. In pharmaceutical manufacturing, dequalinium chloride is the active ingredient in topical antiseptic lozenges.

It is also used in throat sprays and oral rinses targeting oropharyngeal infections. It is formulated into vaginal tablets and pessaries for the treatment of bacterial vaginosis and mixed vaginal infections. In these applications, it acts as a local antimicrobial agent. Personal care formulators incorporate it into antiseptic mouthwashes and medicated skin preparations requiring preservative-level antimicrobial activity.

In research and specialty chemical contexts, it is used as a mitochondria-targeting agent in experimental drug delivery systems. Dequalinium is commercially available primarily as dequalinium chloride. It is supplied as a white to off-white powder. Standard grades include pharmaceutical-grade material meeting USP, BP, or Ph. Eur. specifications for industrial use.

High-purity grades are available for API and finished dosage form manufacturing. Packaging is typically offered in small quantities for R&D through to kilogram-scale lots for commercial production.