Cetylpyridinium chloride

CAS Number
123-03-5
EC Number
204-593-9
Chemical Formula
C21H38N.Cl
Molecular Weight
340.0 g/mol
Abbreviation
CPC

Description

Cetylpyridinium chloride (CAS 123-03-5), commonly abbreviated as CPC, is a quaternary ammonium compound used as an antimicrobial active and preservative across pharmaceutical and personal care manufacturing. It delivers broad-spectrum biocidal activity against bacteria, fungi, and some viruses, making it a go-to active ingredient where surface-active preservation is required for various formulations.

In oral care, CPC is the active ingredient in antiseptic mouthwashes, throat lozenges, and medicated sprays, where it reduces oral bacterial load and controls plaque effectively. Personal care formulators incorporate it into shampoos, skin cleansers, and conditioning products for its combined antimicrobial and surfactant properties in diverse consumer goods.

Pharmaceutical manufacturers use it as a preservative in topical formulations and as an active in over-the-counter antiseptic products subject to specific regulatory monographs. It also functions as a dispersing and emulsifying agent in certain industrial and cosmetic systems where controlled microbial stability is a simultaneous requirement for the product.

Cetylpyridinium chloride is supplied as a white crystalline powder or as an aqueous solution. Standard grades include USP, BP, and Ph. Eur., supporting direct use in regulated applications. These high-purity grades ensure compliance with global pharmacopeia requirements. Technical-grade material is also available for non-regulated industrial uses and general manufacturing needs.

Other Names (Synonyms)

N-hexadecylpyridinium chloride|N-cetylpyridinium chloride|hexadecylpyridinium chloride|1-palmitylpyridinium chloride|1-cetylpyridinium chloride|cetylpyridinium chloride anhydrous|Pristacin|Cepacol|CPC

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 80 °C
Boiling Point 496.25°C (rough estimate)
Density 1.656 g/cm³
Appearance white powder or crystals with a pyridine-like odour
Color White to off-white
Odor Pyridine
Form White Crystalline Powder
Water Solubility 111g/L at 20℃
Vapor Pressure 0Pa at 25℃
Refractive Index 1.6000 (estimate)
Log P 1.71 at 20℃

Documentation

Safety & Handling Learn More

Danger
GHS05· Corrosive GHS06· Toxic GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H301 Toxic if swallowed
H302 Harmful if swallowed
H315 Causes skin irritation
H318 Causes serious eye damage

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Trade & Regulatory

HS Code 2933399990
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