SoleChem

Cetylpyridinium chloride

Surfactants Pharmaceuticals & Healthcare
CAS
123-03-5
EC
204-593-9
Mol. Weight
340.0 g/mol

Description

Cetylpyridinium chloride (CAS 123-03-5), commonly abbreviated as CPC, is a quaternary ammonium compound used as an antimicrobial active and preservative across pharmaceutical and personal care manufacturing.

It delivers broad-spectrum biocidal activity against bacteria, fungi, and some viruses, making it a go-to active ingredient where surface-active preservation is required for various formulations.

In oral care, CPC is the active ingredient in antiseptic mouthwashes, throat lozenges, and medicated sprays, where it reduces oral bacterial load and controls plaque effectively.

Personal care formulators incorporate it into shampoos, skin cleansers, and conditioning products for its combined antimicrobial and surfactant properties in diverse consumer goods.

Pharmaceutical manufacturers use it as a preservative in topical formulations and as an active in over-the-counter antiseptic products subject to specific regulatory monographs.

It also functions as a dispersing and emulsifying agent in certain industrial and cosmetic systems where controlled microbial stability is a simultaneous requirement for the product.

Cetylpyridinium chloride is supplied as a white crystalline powder or as an aqueous solution. Standard grades include USP, BP, and Ph. Eur., supporting direct use in regulated applications.

These high-purity grades ensure compliance with global pharmacopeia requirements. Technical-grade material is also available for non-regulated industrial uses and general manufacturing needs.

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Physical Properties

Melting Point 80 °C
Boiling Point 496.25°C (rough estimate)
Density 1.656 g/cm³
Appearance white powder or crystals with a pyridine-like odour
Color White to off-white
Odor at 100.00?%. pyridine
Form White Crystalline Powder
Water Solubility 111g/L at 20℃
Vapor Pressure 0Pa at 25℃
Refractive Index 1.6000 (estimate)
Log P 1.71 at 20℃

Safety & Handling (Learn More)

Danger GHS05 GHS06 GHS07 GHS09
Hazard Statements
H301 Toxic if swallowed
H302 Harmful if swallowed
H315 Causes skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation
H330 Fatal if inhaled
H335 May cause respiratory irritation
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
Precautionary Statements
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 In case of inadequate ventilation wear respiratory protection.
P316 Get emergency medical help immediately.
P317 Get emergency medical help.
P319 Get medical advice/attention if you feel unwell.
P320 Specific treatment is urgent (see … on this label).
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P316 Get emergency medical help immediately.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 2933399990

Documentation

Other Names

N-hexadecylpyridinium chloride|N-cetylpyridinium chloride|hexadecylpyridinium chloride|1-palmitylpyridinium chloride|1-cetylpyridinium chloride|cetylpyridinium chloride anhydrous|Pristacin|Cepacol|CPC

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