SoleChem

Chlorocresol

Heterocyclic Compounds Coatings, Adhesives, Sealants & Elastomers
CAS
59-50-7
EC
200-431-6
Mol. Weight
142.58 g/mol

Description

Chlorocresol (CAS 59-50-7), also known by the abbreviation PCMC, is a broad-spectrum antimicrobial active used as a preservative and biocide across pharmaceutical, personal care, and industrial formulations.

It delivers effective protection against bacteria, fungi, and yeast at low use concentrations, making it a practical choice for formulators managing microbial challenge across diverse product types.

In pharmaceutical manufacturing, it is an established preservative in topical creams, ointments, and multi-dose injectable preparations where long-term microbial integrity is required for safety.

Personal care formulators incorporate it into lotions, shampoos, and wet wipes to extend shelf life and meet preservation efficacy standards. In coatings, adhesives, and sealants, it functions as a preservative.

It protects water-based systems from microbial degradation during storage and after application. Industrial cutting fluids and metalworking emulsions also use PCMC to suppress bacterial growth during use.

This suppression prevents the compromise of fluid performance and worker conditions. The material is supplied as a white to off-white crystalline powder or flake for easy handling in production.

Standard grades include pharmaceutical-grade material meeting BP and Ph.Eur. specifications, as well as technical grade for industrial preservation applications in various sectors.

Packaging typically ranges from kilogram quantities up to bulk drum supply to suit both compounding and large-scale manufacturing requirements for global chemical distribution and logistics.

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Physical Properties

Melting Point 67 °C
Boiling Point 235 °C
Density 1.37 g/cm³
Flash Point 118 °C
Appearance White (pure) or pink crystalline solid. Crystals turn pink on exposure to air and light. Phenolic odor.
Color White
Form Tablets
Water Solubility 4 g/L (20 ºC)
Vapor Pressure <0.1 hPa (20 °C)
Refractive Index 1.5449 (estimate)
pH 6.5 (1g/l, H2O, 20℃)
Log P 3.100

Safety & Handling (Learn More)

Danger GHS05 GHS07 GHS09 GHS08
Hazard Statements
H302 Harmful if swallowed
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H317 May cause an allergic skin reaction
H318 Causes serious eye damage
H335 May cause respiratory irritation
H373 May causes damage to organs through prolonged or repeated exposure
H400 Very toxic to aquatic life
H412 Harmful to aquatic life with long lasting effects
Precautionary Statements
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P316 Get emergency medical help immediately.
P317 Get emergency medical help.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P333+P317 Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P301+P330+P331 Rinse mouth. Do NOT induce vomiting.
P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29081000
UN Number 3077
ADR Class 9
Packing Group III
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 2

Documentation

Other Names

4-Chloro-3-methylphenol|4-Chloro-m-cresol|p-Chloro-m-cresol|Ottafact|Baktol|Phenol, 4-chloro-3-methyl-|Baktolan|m-Cresol, 4-chloro-|PCMC

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