Chlorphenesin

CAS Number
104-29-0
EC Number
203-192-6

What is Chlorphenesin?

Chlorphenesin (CAS 104-29-0), also known as p-chlorophenyl-alpha-glyceryl ether, is a synthetic antimicrobial active used in cosmetic and pharmaceutical formulations.

Where is Chlorphenesin used?

  • Personal care: preservative in rinse-off and leave-on products including moisturizers, cleansers, and hair care formulations
  • Preservative and biocide that inhibits microbial growth to extend product shelf life
  • Often combined with other preservatives to broaden the antimicrobial spectrum
  • Paraben-free preservation systems: selected for stability and efficacy
  • Pharmaceutical manufacturers incorporate it into topical preparations where controlled microbial protection is required without the regulatory burden of more restricted preservative systems.

Commercial specifications

  • Packaging in kilogram quantities for development use through to bulk supply

Other Names (Synonyms)

P-Chlorophenyl-alpha-glyceryl ether|Glycerol alpha-P-chlorophenyl ether|Chlorphénésine|3-(P-Chlorophenoxy)propane-1,2-diol|3-(P-Chlorophenoxy)-1,2-propanediol|3-(4-Chlorophenoxy)-1,2-propanediol|3-(4-chlorophenoxy)propane-1,2-diol|1,2-Propanediol, 3-(4-chlorophenoxy)-

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What are the physical properties of Chlorphenesin?

Melting Point 78 °C
Boiling Point 290.96°C (rough estimate)
Density 1.2411 (rough estimate)
Color White to Off-White
Form Solid
Water Solubility Slightly soluble in water.
Vapor Pressure 0Pa at 25℃
Refractive Index 1.5470 (estimate)
Log P 1.23 at 23℃

How is Chlorphenesin classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Chlorphenesin?

HS Code 29094990
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