Preservatives & Biocides
REACH
4-Phenylphenol
CAS Number
92-69-3
EC Number
202-179-2
What is 4-Phenylphenol?
4-Phenylphenol (CAS 92-69-3), also known as 4-hydroxybiphenyl, is a hydroxylated biphenyl compound used as a biocide and preservative in personal care, pharmaceutical and food-contact applications.
Where is 4-Phenylphenol used?
- Personal care and cosmetics: incorporated into preservative systems for creams, lotions and rinse-off products
- Pharmaceuticals: intermediate in the synthesis of active ingredients
- Food packaging and food-contact materials: preservative additive
- Industrial disinfectants and surface treatments: biocidal efficacy against bacteria and fungi
- It functions as an antimicrobial agent and antioxidant stabilizer in formulations requiring broad-spectrum protection.
Commercial specifications
- Pharmaceutical intermediates typically meet defined purity thresholds relevant to GMP manufacturing environments.
- Bulk quantities are standard for industrial scale.
Other Names (Synonyms)
[1,1'-Biphenyl]-4-ol|4-HYDROXYBIPHENYL|Biphenyl-4-ol|p-Phenylphenol|4-Biphenylol|p-Hydroxybiphenyl|p-Hydroxydiphenyl|4-Hydroxydiphenyl
What are the physical properties of 4-Phenylphenol?
Melting Point 164-165 °C
Boiling Point 305-308 °C
Density 127 g/cm³ @ Temp: 25 °C
Flash Point 330 °F
Appearance light tan solid (odour threshold detection limit 0.7 ppm)
Color White to slightly yellow
Form Flakes
Water Solubility 0.7 g/L (20 ºC)
Vapor Pressure 0Pa at 25℃
Refractive Index 1.6188 (estimate)
pH 7 (0.7g/l, H2O, 20℃)
Log P 3.6 at 25℃
How is 4-Phenylphenol classified and handled safely? Learn More
Warning
GHS07· Irritant GHS09· Environmental Hazard
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H411 Toxic to aquatic life with long lasting effects
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
Which trade and regulatory codes apply to 4-Phenylphenol?
HS Code 29071900
UN Number 3077
Storage Class 13 - Non Combustible Solids
WGK (Germany) 2