SoleChem

4-Phenylphenol

CAS
92-69-3
EC
202-179-2
Mol. Weight
170.21 g/mol

Description

4-Phenylphenol (CAS 92-69-3), also known as 4-hydroxybiphenyl, is a hydroxylated biphenyl compound used as a biocide and preservative across personal care, pharmaceutical, and food-contact applications.

It functions as an antimicrobial agent and antioxidant stabilizer in formulations requiring broad-spectrum protection against microbial degradation. In personal care and cosmetics, it is incorporated into preservative systems.

This compound is used for creams, lotions, and rinse-off products where microbial contamination control is critical. Pharmaceutical manufacturers use it as an intermediate in the synthesis of active ingredients.

It also serves as a stabilizer in formulations sensitive to oxidative degradation. In food packaging and food-contact materials, it serves as a preservative additive where regulatory compliance governs sourcing.

Industrial disinfectant and surface treatment formulations also rely on it for its biocidal efficacy against bacteria and fungi. 4-Phenylphenol is supplied as a white to off-white crystalline powder or flakes.

Technical and pharmaceutical-grade material is available, with pharmaceutical intermediates typically meeting defined purity thresholds relevant to GMP manufacturing environments. Bulk quantities are standard for industrial scale.

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Physical Properties

Melting Point 164-165 °C
Boiling Point 305-308 °C
Density 127 g/cm³ @ Temp: 25 °C
Flash Point 330 °F
Appearance light tan solid (odour threshold detection limit 0.7 ppm)
Color White to slightly yellow
Form Flakes
Water Solubility 0.7 g/L (20 ºC)
Vapor Pressure 0Pa at 25℃
Refractive Index 1.6188 (estimate)
pH 7 (0.7g/l, H2O, 20℃)
Log P 3.6 at 25℃

Safety & Handling (Learn More)

Warning GHS07 GHS09
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H411 Toxic to aquatic life with long lasting effects
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P391 Collect spillage.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29071900
UN Number 3077
Storage Class 13 - Non Combustible Solids
WGK (Germany) 2

Documentation

Other Names

[1,1'-Biphenyl]-4-ol|4-HYDROXYBIPHENYL|Biphenyl-4-ol|p-Phenylphenol|4-Biphenylol|p-Hydroxybiphenyl|p-Hydroxydiphenyl|4-Hydroxydiphenyl

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