Phenol

CAS Number
108-95-2
EC Number
203-632-7
FEMA Number
FEMA 3223

What is Phenol?

Phenol (CAS 108-95-2), also recognized by its FEMA 3223 designation, is a high-volume industrial chemical used as a building block for resins, pharmaceutical intermediates, and specialty chemicals.

Where is Phenol used?

  • Pharmaceutical manufacturing: key intermediate in synthesis of analgesics, antiseptics, and active pharmaceutical ingredients; preservative in injectable formulations
  • Resin and polymer production: primary feedstock for phenol-formaldehyde resins in adhesives, laminates, and molded industrial components
  • Personal care and cosmetics: pH buffer and antimicrobial agent in topical formulations; precursor of some products for the cosmetics industry, including hair dyes and sunscreens.
  • Textile and leather processing: phenol-derived compounds for dyestuff synthesis and carrier solvent in fiber dyeing
  • It functions as a disinfectant, preservative, and reactive intermediate across manufacturing sectors ranging from polymer production to personal care.
  • Used in chemical peels to remove skin lesions.
  • Used in injections for the treatment of chronic pain or spasticity.

Formulation notes

  • The acid-base reaction with bases generates heat, which may initiate polymerization of the organic compound.

Typical specification

  • Pure phenol is a whitish solid, whereas the commercial product is a liquid.
  • Available as a 45°C molten liquid, 60°C molten liquid, 85% solution at 45°C, and 85% solution.
  • Completely miscible with water above 68.4 °C.

Regulatory status

  • Suspected of causing genetic defects (H341).
  • Toxic if inhaled (H331).
  • May cause damage to organs through prolonged or repeated exposure (H373).

Technical content is compiled and updated by the SoleChem product team from public technical sources; the certificate of analysis (COA) governs product-specific specifications.

Other Names (Synonyms)

phenol homopolymer|phenol alcohol|phenic alcohol|phenic acid|phenic|monohydroxy benzene|hydroxy-benzene|carbolic oil

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What are the physical properties of Phenol?

Melting Point 40.91 °C
Boiling Point 181.75 °C @ Press: 760.0 Torr
Density 1.071 g/cm³
Flash Point 175 °F
Appearance Phenol is a colorless to light-pink, crystalline solid. Sweet, acrid odor. Phenol liquefies by mixing with about 8% water. The Odor Threshold in air is 0.04 ppm and in water is 7.9 ppm.
Color faintly yellow
Odor Sweet, medicinal odor detectable at 0.06 ppm
Form liquid
Water Solubility 8 g/100 mL
Vapor Pressure 0.09 psi ( 55 °C)
Refractive Index n 20/D 1.53
pH 3.0-6.0 (25℃, 0.5M in H2O)
Log P 1.47 at 30℃

How is Phenol classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS06· Toxic GHS08· Health Hazard GHS09· Environmental Hazard GHS07· Irritant

Hazard Statements

H301 Toxic if swallowed
H302 Harmful if swallowed
H311 Toxic in contact with skin
H314 Causes severe skin burns and eye damage

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.

Which trade and regulatory codes apply to Phenol?

HS Code 29071100
UN Number 2821
ADR Class 6.1
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 2
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