Phenacetin
Description
Phenacetin (CAS 62-44-2), also known as p-Acetophenetidide, is a synthetic acetamide compound used as a pharmaceutical intermediate and chemical building block across multiple industrial sectors.
It functions as an antioxidant stabilizer and processing aid in polymer and specialty chemical manufacturing. In plastics and polymer processing, it acts as a stabilizer to inhibit oxidative degradation during high-temperature compounding.
The pharmaceutical and fine chemical industries source it as an intermediate for synthesizing active compounds and research-grade formulations. In textile and leather processing, it is used as a surface modifier and auxiliary agent.
These applications help to improve dye uptake and substrate compatibility. Personal care formulators have historically incorporated it into preservation and stabilization systems within cosmetic manufacturing processes.
The product is supplied as a white crystalline powder in both technical and pharmaceutical-grade specifications. Standard grades include USP and BP, with pharmaceutical-grade material subject to tighter purity thresholds.
These thresholds are typically above 99% for high-purity applications. Bulk quantities are available in multi-kilogram and metric-ton packaging, with smaller quantities offered for laboratory and formulation development use.
Physical Properties
| Melting Point | 134-135 °C |
| Boiling Point | 132 °C / 4mmHg |
| Density | 1.2404 g/cm³ |
| Flash Point | 2°C |
| Appearance | white crystalline powder |
| Color | White |
| Form | powder |
| Water Solubility | 0.076 g/100 mL |
| Refractive Index | 1.5710 |
| Log P | 1.580 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29251995 |
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 3 |
Documentation
Other Names
N-(4-ethoxyphenyl)acetamide|p-Acetophenetidide|Acetamide, N-(4-ethoxyphenyl)-|PENACETIN
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