SoleChem

Phenacetin

CAS
62-44-2
EC
200-533-0
Mol. Weight
179.22 g/mol

Description

Phenacetin (CAS 62-44-2), also known as p-Acetophenetidide, is a synthetic acetamide compound used as a pharmaceutical intermediate and chemical building block across multiple industrial sectors.

It functions as an antioxidant stabilizer and processing aid in polymer and specialty chemical manufacturing. In plastics and polymer processing, it acts as a stabilizer to inhibit oxidative degradation during high-temperature compounding.

The pharmaceutical and fine chemical industries source it as an intermediate for synthesizing active compounds and research-grade formulations. In textile and leather processing, it is used as a surface modifier and auxiliary agent.

These applications help to improve dye uptake and substrate compatibility. Personal care formulators have historically incorporated it into preservation and stabilization systems within cosmetic manufacturing processes.

The product is supplied as a white crystalline powder in both technical and pharmaceutical-grade specifications. Standard grades include USP and BP, with pharmaceutical-grade material subject to tighter purity thresholds.

These thresholds are typically above 99% for high-purity applications. Bulk quantities are available in multi-kilogram and metric-ton packaging, with smaller quantities offered for laboratory and formulation development use.

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Physical Properties

Melting Point 134-135 °C
Boiling Point 132 °C / 4mmHg
Density 1.2404 g/cm³
Flash Point 2°C
Appearance white crystalline powder
Color White
Form powder
Water Solubility 0.076 g/100 mL
Refractive Index 1.5710
Log P 1.580

Safety & Handling (Learn More)

Danger GHS07 GHS08
Hazard Statements
H302 Harmful if swallowed
H341 Suspected of causing genetic defects
H350 May cause cancer
H362 May cause harm to breast-fed children
H370 Causes damage to organs
H372 Causes damage to organs through prolonged or repeated exposure
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy and while nursing.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P318 IF exposed or concerned, get medical advice.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P301+P317 Get emergency medical help.
P308+P316 Get emergency medical help immediately.

Trade & Regulatory

HS Code 29251995
UN Number 3077
ADR Class 9
Packing Group III
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 3

Documentation

Other Names

N-(4-ethoxyphenyl)acetamide|p-Acetophenetidide|Acetamide, N-(4-ethoxyphenyl)-|PENACETIN

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