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Phenylacetonitrile

Agrochemicals Pharmaceuticals & Healthcare
CAS
140-29-4
EC
205-410-5
Mol. Weight
117.15 g/mol

Description

Phenylacetonitrile (CAS 140-29-4), also known as benzyl cyanide, is a key building block in pharmaceutical and fine chemical synthesis. It serves as a reactive intermediate for constructing complex molecular frameworks.

The compound is utilized through condensation, alkylation, and hydrolysis reactions. In pharmaceutical manufacturing, it is used to synthesize active ingredients including analgesics, antihistamines, and cardiovascular compounds.

The nitrile group enables essential downstream functional group transformations. Agrochemical producers rely on it as a precursor in the synthesis of certain insecticides and herbicides for crop protection.

Flavor and fragrance chemists use it as a starting material for phenylacetic acid derivatives. These derivatives contribute rose and honey-like notes to finished fragrance compositions and consumer products.

It also functions as a specialty solvent in select chemical processes where its polarity and reactivity profile suit specific reaction conditions. The material is supplied as a clear to pale yellow liquid.

Standard packaging options include drum and IBC containers for industrial logistics. It is available in technical grade for synthesis applications, with higher-purity specifications offered for pharmaceutical intermediate use.

Buyers should confirm purity levels and residual impurity profiles against their internal quality standards. This is particularly important when sourcing for regulated manufacturing environments and high-stakes production.

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Safety & Handling (Learn More)

Danger GHS06 GHS07 GHS08
Hazard Statements
H301 Toxic if swallowed [Danger Acute toxicity, oral]
H311 Toxic in contact with skin [Danger Acute toxicity, dermal]
H319 Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H330 Fatal if inhaled [Danger Acute toxicity, inhalation]
H372 Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]

Documentation

Other Names

benzyl nitrile|benzyl cyanide|alpha-tolunitrile|alpha-cyanotoluene|2-phenylacetonitrile|(cyanomethyl)benzene|Acetonitrile, phenyl-|ω-Cyanotoluene

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