P-tolunitrile

CAS Number
104-85-8
EC Number
203-244-8
Chemical Formula
C8H7N
Molecular Weight
117.15 g/mol

Description

P-tolunitrile (CAS 104-85-8), also known as 4-cyanotoluene, is an aromatic nitrile compound used as a chemical intermediate in the synthesis of active ingredients and specialty chemicals. It functions primarily as a building block in pharmaceutical, fragrance, and agrochemical manufacturing rather than as a finished product. In pharmaceutical synthesis, it serves as a precursor to active pharmaceutical ingredients.

The nitrile group undergoes hydrolysis, reduction, or cyclization to produce target molecules. Fragrance manufacturers use it as an intermediate in the production of aromatic compounds where controlled functionalization is required. In agrochemical production, it contributes to the synthesis of herbicides and fungicides through established nitrile chemistry pathways. Industrial cleaning and biocide formulations may incorporate derivatives produced from this intermediate.

P-tolunitrile is supplied as a liquid at ambient conditions, with purity grades typically ranging from technical to high-purity for pharmaceutical and specialty chemical applications. It is available in standard packaging configurations including drums and intermediate bulk containers suited to industrial procurement volumes. Buyers should confirm purity specifications and impurity profiles directly with the supplier.

This ensures suitability for regulated synthesis processes. The material is handled according to standard industrial safety protocols for aromatic nitriles to maintain product integrity and operational safety.

Other Names (Synonyms)

4-METHYLBENZONITRILE|4-Cyanotoluene|4-Tolunitrile|p-Methylbenzonitrile|Benzonitrile, 4-methyl-|p-Cyanotoluene|p-Toluonitrile|p-Tolylnitrile

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 29.5 °C
Boiling Point 220 °C
Density 0.981 g/mL at 25 °C(lit.)
Flash Point 185 °F
Appearance beige solid
Color Clear
Form Viscous Liquid
Water Solubility <0.1 g/100 mL at 17 ºC
Refractive Index 1.5285-1.5305

Documentation

Safety & Handling Learn More

Danger
GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335 May cause respiratory irritation
H412 Harmful to aquatic life with long lasting effects

Precautionary Statements

P233 Keep container tightly closed.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.

Trade & Regulatory

HS Code 29269095
Storage Class 11 - Combustible Solids
WGK (Germany) 2
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